Hypoxia induces immunosuppression, metastasis and drug resistance in pancreatic cancers
H Zhang, K Cao, J Xiang, M Zhang, M Zhu, Q Xi - Cancer Letters, 2023 - Elsevier
Pancreatic cancer is one of the common malignant tumors of the digestive system and is
known as the “king of cancers”. It is extremely difficult to diagnose at an early stage, the …
known as the “king of cancers”. It is extremely difficult to diagnose at an early stage, the …
c-Met pathway in human malignancies and its targeting by natural compounds for cancer therapy
CD Mohan, MK Shanmugam, SGS Gowda… - Phytomedicine, 2024 - Elsevier
Background c-MET is a receptor tyrosine kinase which is classically activated by HGF to
activate its downstream signaling cascades such as MAPK, PI3K/Akt/mTOR, and STAT3 …
activate its downstream signaling cascades such as MAPK, PI3K/Akt/mTOR, and STAT3 …
Hypoxia-induced OSBPL10 accelerates pancreatic cancer progression through CNBP sequestration
Y Huang, R Zhang, S Fan, M Shi, X Tang, X Wang… - 2024 - researchsquare.com
Purpose Given oxysterol binding protein like 10's (OSBPL10) known involvement in lipid
transport and oncogenic activity in other tumors, we aimed to elucidate the mechanism …
transport and oncogenic activity in other tumors, we aimed to elucidate the mechanism …
Lactylation-Associated Subtypes and Signature Genes for Diagnosis, Risk Prediction and Treatment of Pancreatic Cancer
S Luo, N Xie, J Song, E Zheng, M Jiang - Risk Prediction and Treatment of … - papers.ssrn.com
Background Lactylation plays an important role in tumorigenesis; however, its mechanism of
action in pancreatic cancer (PC) remains unknown. Methods The PC-related TCGA-PAAD …
action in pancreatic cancer (PC) remains unknown. Methods The PC-related TCGA-PAAD …