Arousal from sleep: implications for obstructive sleep apnea pathogenesis and treatment

DJ Eckert, MK Younes - Journal of Applied Physiology, 2014 - journals.physiology.org
Historically, brief awakenings from sleep (cortical arousals) have been assumed to be vitally
important in restoring airflow and blood-gas disturbances at the end of obstructive sleep …

Clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apnea

Positive Airway Pressure Titration Task Force … - Journal of Clinical …, 2008 - jcsm.aasm.org
Positive airway pressure (PAP) devices are used to treat patients with sleep related
breathing disorders (SRBDs), including obstructive sleep apnea (OSA). After a patient is …

Nasal continuous positive airway pressure treatment: current realities and future

M Berthon-Jones, S Lawrence, CE Sullivan… - Sleep, 1996 - academic.oup.com
Nasal continuous positive airway pressure (CPAP) is a highly effective treatment for
obstructive sleep apnea syndrome. The apnea/hypopnea index (AHI) is reduced 10-fold, but …

Pharyngeal critical pressure in patients with obstructive sleep apnea syndrome: clinical implications

E Sforza, C Petiau, T Weiss, A Thibault… - American journal of …, 1999 - atsjournals.org
Current evidence suggests that patients with obstructive sleep apnea (OSA) may have
greater pharyngeal critical pressure (Pcrit), which reflects the increase in upper airway …

Magnetic resonance imaging of the upper airway: effects of propofol anesthesia and nasal continuous positive airway pressure in humans

M Mathru, O Esch, J Lang, ME Herbert… - The Journal of the …, 1996 - pubs.asahq.org
Background Anesthetic agents inhibit the respiratory activity of upper airway muscles more
than the diaphragm, creating a potential for narrowing or complete closure of the pharyngeal …

Effects of esophageal pressure monitoring on sleep architecture

RD Chervin, MS Aldrich - American journal of respiratory and critical …, 1997 - atsjournals.org
Esophageal pressure (Pes) monitoring can be performed during polysomnography with a
thin, water-filled catheter connected to a transducer. The resulting quantitative assessment …

Obstructive sleep apnea and thoracic aorta dissection

G Sampol, O Romero, A Salas, JL Tovar… - American journal of …, 2003 - atsjournals.org
Obstructive sleep apnea syndrome (OSAS) is a process that is associated with the
development of arterial hypertension, the main risk factor for aortic dissection and during …

Assessment of inspiratory flow limitation invasively and noninvasively during sleep

SA Clark, CR Wilson, M Satoh, D Pegelow… - American journal of …, 1998 - atsjournals.org
To define the standard of airway flow limitation, pharyngeal pressure and flow rate were
measured during wakefulness and sleep in seven habitual snorers with widely varying …

Respiratory effort during obstructive sleep apnea: role of age and sleep state

J Krieger, E Sforza, A Boudewijns, M Zamagni… - Chest, 1997 - Elsevier
Objective To evaluate the patients' individual characteristics predictive of the degree of
respiratory effort developed during obstructive sleep apneas (OSAs). Design Prospective …

CPAP pressure for prediction of oral appliance treatment response in obstructive sleep apnea

K Sutherland, CL Phillips, A Davies… - Journal of Clinical …, 2014 - jcsm.aasm.org
Study Objectives: Mandibular advancement splints (MAS) are often preferred to CPAP
treatment for OSA but are not always equally efficacious. High therapeutic CPAP pressure …