The immunology of type 1 diabetes

KC Herold, T Delong, AL Perdigoto, N Biru… - Nature Reviews …, 2024 - nature.com
Following the seminal discovery of insulin a century ago, treatment of individuals with type 1
diabetes (T1D) has been largely restricted to efforts to monitor and treat metabolic glucose …

Translation of cell therapies to treat autoimmune disorders

JM Mehta, SC Hiremath, C Chilimba, A Ghasemi… - Advanced Drug Delivery …, 2023 - Elsevier
Autoimmune diseases are a diverse and complex set of chronic disorders with a substantial
impact on patient quality of life and a significant global healthcare burden. Current …

Incidence of type 2 diabetes before and during the COVID-19 pandemic in Naples, Italy: a longitudinal cohort study

R Izzo, D Pacella, V Trimarco, MV Manzi… - …, 2023 - thelancet.com
Background The association of COVID-19 with the development of new-onset diabetes has
been recently investigated by several groups, yielding controversial results. Population …

New-onset diabetes mellitus in COVID-19: a scoping review

A Pantea Stoian, IC Bica, T Salmen, W Al Mahmeed… - Diabetes Therapy, 2024 - Springer
Introduction The coronavirus disease 2019 (COVID-19) pandemic became superimposed
on the pre-existing obesity and diabetes mellitus (DM) pandemics. Since COVID-19 infection …

Incidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people

K Taylor, S Eastwood, V Walker, G Cezard… - The Lancet Diabetes & …, 2024 - thelancet.com
Background Some studies have shown that the incidence of type 2 diabetes increases after
a diagnosis of COVID-19, although the evidence is not conclusive. However, the effects of …

The INNODIA Type 1 Diabetes Natural History Study: a European cohort of newly diagnosed children, adolescents and adults

ML Marcovecchio, AEJ Hendriks, C Delfin, T Battelino… - Diabetologia, 2024 - Springer
Aims/hypothesis Type 1 diabetes is an heterogenous condition. Characterising factors
explaining differences in an individual's clinical course and treatment response will have …

Incidence of Type 1 Diabetes in Children Has Fallen to Pre–COVID-19 Pandemic Levels: A Population-Wide Analysis From Scotland

W Berthon, SJ McGurnaghan, LAK Blackbourn… - Diabetes …, 2024 - Am Diabetes Assoc
We previously reported in Diabetes Care (1) that the incidence of type 1 diabetes among
children aged 0–14 years in Scotland during 2020–2021 was 20% higher than the 7-year …

Elucidating the underlying mechanisms of the marked increase in childhood type 1 diabetes during the COVID-19 pandemic—the diabetes pandemic

C Kamath, RW Holl, J Rosenbauer - JAMA Network Open, 2023 - jamanetwork.com
In a systematic review and meta-analysis in JAMA Network Open, D'Souza et al1 compared
changes in the incidence of diabetes (type 1 and type 2) and the proportion of diabetic …

The relationship between SARS-CoV-2 infection and type 1 diabetes mellitus

C Debuysschere, MP Nekoua, EK Alidjinou… - Nature Reviews …, 2024 - nature.com
Environmental factors, in particular viral infections, are thought to have an important role in
the pathogenesis of type 1 diabetes mellitus (T1DM). The COVID-19 pandemic reinforced …

Trends in the Incidence of Type 1 Diabetes in European Children and Adolescents from 1994 to 2022: A Systematic Review and Meta‐Analysis

MC Ruiz-Grao, A Díez-Fernández, AE Mesas… - Pediatric …, 2024 - Wiley Online Library
Aim. To assess the incidence trends in type 1 diabetes among children and adolescents
across Europe during the period from 1994 to 2022 using a systematic methodology …