Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …

Patients with cystic fibrosis (CF) are repeatedly exposed to antibiotics, especially during the
pulmonary exacerbations of the disease. However, the available therapeutic strategies are …

Recurrent and chronic bacterial infections are common in people with cystic fibrosis (CF)
and contribute to lung function decline. Antibiotics are the mainstay in the treatment of …

This review guides the reader through the current understanding of the dynamic changes
that occur within the cystic fibrosis (CF) lung that allow Pseudomonas aeruginosa to become …

Bacterial infections in the respiratory tract are considered as one of the major challenges to
the public health worldwide. Pulmonary delivery is an attractive approach in the …

Characterized by impaired mucus transport and subsequent enhanced colonization of
bacteria, pulmonary infection causes major morbidity and mortality in patients with cystic …

Lung diseases continue to draw considerable attention from biomedical and public health
care agencies. The lung with the largest epithelial surface area is continuously exposed to …

Pulmonary bacterial infections present a significant health risk to those with chronic
respiratory diseases (CRDs) including cystic fibrosis (CF) and chronic-obstructive pulmonary …

For those born with cystic fibrosis (CF), hyper-concentrated mucus with a dysfunctional
structure significantly impacts CF airways, providing a perfect environment for bacterial …

Airway mucus dysfunction and impaired immunological defenses are hallmarks of several
lung diseases, including asthma, cystic fibrosis, and chronic obstructive pulmonary …