Organelles perform critical biological functions due to their distinct molecular composition
and internal environment. Disorders in organelles or their interacting networks have been …

Mitochondria play a crucial part in the cell's ability to adapt to the changing
microenvironments and their dysfunction is associated with an extensive array of illnesses …

Drug delivery systems (DDSs) have emerged to help delivering the required cargo into the
region of the tumor, achieving the objectives of extenuating the potential damage to the body …

Mitochondria-targeting peptides represent an emergent tool for cancer inhibition. Here
supramolecular assemblies of novel amphiphilic cell-penetrating peptides for targeting …

Nanocarriers have emerged as a promising cancer drug delivery strategy. Multi-drug
resistance caused by overexpression of multiple-drug excretion transporters in tumor cells is …

Primary tumor metastasis remains to be a tough obstacle for clinical breast cancer treatment.
Since evidences have shown that mitochondria play a crucial role in tumor metastasis, we …

Mitochondria play a central role in metabolic homeostasis, and dysfunction of this organelle
underpins the etiology of many heritable and aging-related diseases. Tetrapeptides with …

Background Known as the main site of ATP production and intrinsic apoptosis regulator,
mitochondria play vital roles in physiological functions and pathological progression …

Mitochondria are multifunctional subcellular organelles whose operations encompass
energy production, signal transduction, and metabolic regulation. Given their wide range of …

As a major clinical tumor chemotherapeutic burden, multidrug resistance (MDR) is often a
result of up-regulation of P-glycoprotein (P-gp), which strongly enhances anticancer drug …