The ubiquitin-proteasome system and learning-dependent synaptic plasticity–A 10 year update
Over 25 years ago, a seminal paper demonstrated that the ubiquitin-proteasome system
(UPS) was involved in activity-dependent synaptic plasticity. Interest in this topic began to …
(UPS) was involved in activity-dependent synaptic plasticity. Interest in this topic began to …
[HTML][HTML] A novel autism-associated UBLCP1 mutation impacts proteasome regulation/activity
J Soueid, Z Hamze, J Bedran, M Chahrour… - Translational …, 2023 - nature.com
The landscape of autism spectrum disorder (ASD) in Lebanon is unique because of high
rates of consanguinity, shared ancestry, and increased remote consanguinity. ASD …
rates of consanguinity, shared ancestry, and increased remote consanguinity. ASD …
Neuronal and astrocytic protein degradation are critical for fear memory formation
Strong evidence has implicated proteasome-mediated protein degradation in the memory
consolidation process. However, due to the use of pharmacological approaches, the cell …
consolidation process. However, due to the use of pharmacological approaches, the cell …
Phosphorylation of RPT6 controls its ability to bind DNA and regulate gene expression in the hippocampus of male rats during memory formation
K Farrell, A Auerbach, M Musaus… - Journal of …, 2024 - Soc Neuroscience
Memory formation requires coordinated control of gene expression, protein synthesis, and
ubiquitin–proteasome system (UPS)-mediated protein degradation. The catalytic component …
ubiquitin–proteasome system (UPS)-mediated protein degradation. The catalytic component …
Estradiol regulates local synthesis of synaptic proteome via sex-specific mechanisms.
P Raval, H Rae, RRR Duarte, IA Watson, K Sellers… - bioRxiv, 2023 - biorxiv.org
Estrogens, specifically 17β-estradiol (estradiol), can modulate synaptic function by
regulating the expression and localisation of synaptic proteins. However, the mechanisms …
regulating the expression and localisation of synaptic proteins. However, the mechanisms …
[PDF][PDF] Estradiol regulates local synthesis of synaptic proteome via sex-specific mechanisms.
P Srivastava - storage.prod.researchhub.com
Abstract Estrogens, specifically 17³-estradiol (estradiol), can modulate synaptic function by
regulating the expression and localisation of synaptic proteins. However, the mechanisms …
regulating the expression and localisation of synaptic proteins. However, the mechanisms …