Tendon and cytokine marker expression by human bone marrow mesenchymal stem cells in a hyaluronate/poly-lactic-co-glycolic acid (PLGA)/fibrin three-dimensional …

MC Ciardulli, L Marino, J Lovecchio, E Giordano… - Cells, 2020 - mdpi.com
We developed a (three-dimensional) 3D scaffold, we named HY-FIB, incorporating a force-
transmission band of braided hyaluronate embedded in a cell localizing fibrin hydrogel and …

In vitro production of mouse morphological sperm in artificial testis bioengineered by 3D printing of extracellular matrix

Z Bashiri, M Gholipourmalekabadi, R Falak… - International Journal of …, 2022 - Elsevier
Since autologous stem cell transplantation is prone to cancer recurrence, in vitro sperm
production is regarded a safer approach to fertility preservation. In this study, the …

Crosslinkable hydrogels derived from cartilage, meniscus, and tendon tissue

J Visser, PA Levett, NCR te Moller, J Besems… - … engineering part A, 2015 - liebertpub.com
Decellularized tissues have proven to be versatile matrices for the engineering of tissues
and organs. These matrices usually consist of collagens, matrix-specific proteins, and a set …

Molecular regulation of tendon cell fate during development

AH Huang, HH Lu, R Schweitzer - Journal of Orthopaedic …, 2015 - Wiley Online Library
Although there have been several advances identifying novel mediators of tendon induction,
differentiation, and patterning, much of the basic landscape of tendon biology from …

Decellularized tendon matrix membranes prevent post-surgical tendon adhesion and promote functional repair

M Tao, F Liang, J He, W Ye, R Javed, W Wang, T Yu… - Acta Biomaterialia, 2021 - Elsevier
Adhesion often occurs after tendon injury, and results in sliding disorder and movement
limitation with no ideal solution for it in clinic. In this study, an anti-adhesion membrane, ie …

Mechanically and biologically promoted cell-laden constructs generated using tissue-specific bioinks for tendon/ligament tissue engineering applications

S Chae, YJ Choi, DW Cho - Biofabrication, 2022 - iopscience.iop.org
Tendon and ligament tissues provide stability and mobility crucial for musculoskeletal
function, but are particularly prone to injury. Owing to poor innate healing capacity, the …

Tendon tissue engineering: Current progress towards an optimized tenogenic differentiation protocol for human stem cells

I Donderwinkel, RS Tuan, NR Cameron, JE Frith - Acta Biomaterialia, 2022 - Elsevier
Tendons are integral to our daily lives by allowing movement and locomotion but are
frequently injured, leading to patient discomfort and impaired mobility. Current clinical …

Harnessing magnetic-mechano actuation in regenerative medicine and tissue engineering

LJ Santos, RL Reis, ME Gomes - Trends in biotechnology, 2015 - cell.com
Mechanical stimulus is of upmost importance in tissues developmental and regeneration
processes as well as in maintaining body homeostasis. Classical physiological reactions …

The utilization of decellularized tendon slices to provide an inductive microenvironment for the proliferation and tenogenic differentiation of stem cells

LJ Ning, YJ Zhang, Y Zhang, Q Qing, YL Jiang… - Biomaterials, 2015 - Elsevier
The extracellular matrix (ECM) microenvironment for the stem cell niches, including but not
limited to the biochemical composition, matrix topography, and stiffness, is crucial to stem …

A bioreactor system for in vitro tendon differentiation and tendon tissue engineering

DW Youngstrom, I Rajpar, DL Kaplan… - Journal of Orthopaedic …, 2015 - Wiley Online Library
There is significant clinical demand for functional tendon grafts in human and veterinary
medicine. Tissue engineering techniques combining cells, scaffolds, and environmental …