Engineering stem cell-derived extracellular matrices: decellularization, characterization, and biological function

S Sart, R Jeske, X Chen, T Ma, Y Li - Tissue Engineering Part B …, 2020 - liebertpub.com
Stem cells, including mesenchymal stem cells and pluripotent stem cells, have attracted
considerable attention in tissue engineering and regenerative medicine primarily because of …

Research progress on the biological modifications of implant materials in 3D printed intervertebral fusion cages

S Li, Y Huan, B Zhu, H Chen, M Tang, Y Yan… - Journal of Materials …, 2022 - Springer
Anterior spine decompression and reconstruction with bone grafts and fusion is a routine
spinal surgery. The intervertebral fusion cage can maintain intervertebral height and provide …

Anatomical region-dependent enhancement of 3-dimensional chondrogenic differentiation of human mesenchymal stem cells by soluble meniscus extracellular matrix

BB Rothrauff, K Shimomura, R Gottardi, PG Alexander… - Acta biomaterialia, 2017 - Elsevier
Extracellular matrix (ECM) derived from decellularized tissues has been found to promote
tissue neogenesis, most likely mediated by specific biochemical and physical signaling …

Region-specific effect of the decellularized meniscus extracellular matrix on mesenchymal stem cell–based meniscus tissue engineering

K Shimomura, BB Rothrauff… - The American journal of …, 2017 - journals.sagepub.com
Background: The meniscus is the most commonly injured knee structure, and surgical repair
is often ineffective. Tissue engineering–based repair or regeneration may provide a needed …

Tendon‐derived extracellular matrix induces mesenchymal stem cell tenogenesis via an integrin/transforming growth factor‐β crosstalk‐mediated mechanism

D Wang, CCM Pun, S Huang, TCM Tang… - The FASEB …, 2020 - Wiley Online Library
Abstract Treatment of tendon injuries is challenging. To develop means to augment tendon
regeneration, we have previously prepared a soluble, low immunogenic (DNA‐free), tendon …

Tenogenesis of bone marrow-, adipose-, and tendon-derived stem cells in a dynamic bioreactor

DW Youngstrom, JE LaDow… - Connective tissue research, 2016 - Taylor & Francis
Tendons are frequently damaged and fail to regenerate, leading to pain, loss of function,
and reduced quality of life. Mesenchymal stem cells (MSCs) possess clinically useful tissue …

Mesenchymal stem cells in soft tissue regenerative medicine: a comprehensive review

A Rehman, A Nigam, L Laino, D Russo, C Todisco… - Medicina, 2023 - mdpi.com
Soft tissue regeneration holds significant promise for addressing various clinical challenges,
ranging from craniofacial and oral tissue defects to blood vessels, muscle, and fibrous tissue …

Efficacy of thermoresponsive, photocrosslinkable hydrogels derived from decellularized tendon and cartilage extracellular matrix for cartilage tissue engineering

BB Rothrauff, L Coluccino, R Gottardi… - Journal of tissue …, 2018 - Wiley Online Library
Tissue engineering using adult mesenchymal stem cells (MSCs), a promising approach for
cartilage repair, is highly dependent on the nature of the matrix scaffold. Thermoresponsive …

Enthesis tissue engineering: biological requirements meet at the interface

I Calejo, R Costa-Almeida, RL Reis… - Tissue Engineering Part …, 2019 - liebertpub.com
Tendon-to-bone interface (enthesis) exhibits a complex multiscale architectural and
compositional organization maintained by a heterogeneous cellular environment …

[HTML][HTML] Tendon stem/progenitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling

S Tarafder, E Chen, Y Jun, K Kao, KH Sim… - The FASEB …, 2017 - ncbi.nlm.nih.gov
Tendon stem/progenitor cells (TSCs) have been found in different anatomic locations and
showed a promising regenerative potential. We identified a role of TSCs in the regulation of …