Human adipose tissue‐derived tenomodulin positive subpopulation of stem cells: a promising source of tendon progenitor cells

AI Gonçalves, PM Gershovich… - Journal of tissue …, 2018 - Wiley Online Library
Cell‐based therapies are of particular interest for tendon and ligament regeneration given
the low regenerative potential of these tissues. Adipose tissue is an abundant source of stem …

Growth factor-mediated tenogenic induction of multipotent mesenchymal stromal cells is altered by the microenvironment of tendon matrix

SP Roth, S Schubert, P Scheibe, C Groß… - Cell …, 2018 - journals.sagepub.com
Age-related degenerative changes in tendon tissue represent a common cause for acute
tendon pathologies. Although the regenerative potential of multipotent mesenchymal stromal …

Fabrication of centimeter-sized 3D constructs with patterned endothelial cells through assembly of cell-laden microbeads as a potential bone graft

G Yang, B Mahadik, JY Choi, RY Justine, T Mollot… - Acta biomaterialia, 2021 - Elsevier
Modular tissue engineering is a promising biofabrication strategy to create engineered bone
grafts in a bottom-up manner, in which cell-laden micro-modules are prepared as basic …

Equiaxial strain modulates adipose-derived stem cell differentiation within 3D biphasic scaffolds towards annulus fibrosus

M Elsaadany, K Winters, S Adams, A Stasuk, H Ayan… - Scientific Reports, 2017 - nature.com
Recurrence of intervertebral disc (IVD) herniation is the most important factor leading to
chronic low back pain and subsequent disability after discectomy. Efficacious annulus …

Application of a hyperelastic 3D printed scaffold for mesenchymal stem cell-based fabrication of a bizonal tendon enthesis-like construct

R Gottardi, K Moeller, R Di Gesù, RS Tuan… - Frontiers in …, 2021 - frontiersin.org
After surgical tendon repair, the tendon-to-bone enthesis often does not regenerate, which
leads to high numbers of rupture recurrences. To remedy this, tissue engineering techniques …

[HTML][HTML] Decellularized porcine Achilles tendon induces anti-inflammatory macrophage phenotype in vitro and tendon repair in vivo

AD Eren, R Sinha, ED Eren, Y Huipin, S Gulce-Iz… - Journal of Immunology …, 2020 - Elsevier
Decellularized tissues and organs from animal sources are widely used in regenerative
medicine and tissue engineering. However, in tendon tissue engineering there is limitation …

Efficacy of adipose-derived mesenchymal stem cells and stromal vascular fraction alone and combined to biomaterials in tendinopathy or tendon injury: Systematic …

L Senesi, F De Francesco, A Marchesini, PP Pangrazi… - Medicina, 2023 - mdpi.com
Background and Objectives: Tendon injury and tendinopathy are among the most frequent
musculoskeletal diseases and represent a challenging issue for surgeons as well as a great …

Stem cell applications and tenogenic differentiation strategies for tendon repair

Z Yuan, H Yu, H Long, Y Dai, L Shi, J Zhao… - Stem Cells …, 2023 - Wiley Online Library
Tendons are associated with a high injury risk because of their overuse and age‐related
tissue degeneration. Thus, tendon injuries pose great clinical and economic challenges to …

Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration

T Tu, Y Shi, B Zhou, X Wang, W Zhang… - NPJ Regenerative …, 2023 - nature.com
Our previous work demonstrated the tendon-derived extracellular matrix (ECM) extracts as
vital niches to specifically direct mesenchymal stem cells towards tenogenic differentiation …

Physical regulation of stem cells differentiation into teno-lineage: current strategies and future direction

JL Chen, W Zhang, ZY Liu, BC Heng… - Cell and Tissue …, 2015 - Springer
Tendon injuries are commonly encountered in the clinic, disrupting the patient's normal
work/life routine and damaging the career life of athletes. Currently, there is still no effective …