Gut microbiota and cardiovascular disease: opportunities and challenges
Coronary artery disease (CAD) is the most common health problem worldwide and remains
the leading cause of morbidity and mortality. Over the past decade, it has become clear that …
the leading cause of morbidity and mortality. Over the past decade, it has become clear that …
Macrophage death and defective inflammation resolution in atherosclerosis
I Tabas - Nature Reviews Immunology, 2010 - nature.com
A key event in atherosclerosis is a maladaptive inflammatory response to subendothelial
lipoproteins. A crucial aspect of this response is a failure to resolve inflammation, which …
lipoproteins. A crucial aspect of this response is a failure to resolve inflammation, which …
Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy
JE McLaren, DR Michael, TG Ashlin, DP Ramji - Progress in lipid research, 2011 - Elsevier
Cardiovascular disease is the biggest killer globally and the principal contributing factor to
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …
Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation
EC Aguilar, AJ Leonel, LG Teixeira, AR Silva… - Nutrition, Metabolism …, 2014 - Elsevier
Background & aims Butyrate is a four-carbon fatty acid that presents anti-inflammatory, anti-
oxidative and apoptotic properties in colon and several cell lines. Because atherosclerosis …
oxidative and apoptotic properties in colon and several cell lines. Because atherosclerosis …
CD36 and macrophages in atherosclerosis
S Collot-Teixeira, J Martin… - Cardiovascular …, 2007 - academic.oup.com
CD36 is a multi-ligand scavenger receptor present on the surface of a number of cells such
as platelets, monocytes/macrophages, endothelial and smooth muscle cells. Monocyte …
as platelets, monocytes/macrophages, endothelial and smooth muscle cells. Monocyte …
Crosstalk between cholesterol metabolism and psoriatic inflammation
L Luo, Y Guo, L Chen, J Zhu, C Li - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a chronic autoinflammatory skin disease associated with multiple comorbidities,
with a prevalence ranging from 2 to 3% in the general population. Decades of preclinical …
with a prevalence ranging from 2 to 3% in the general population. Decades of preclinical …
Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation
IMJ Wolfs, MMPC Donners… - Thrombosis and …, 2011 - thieme-connect.com
The phenotype of macrophages in atherosclerotic lesions can vary dramatically, from a large
lipid laden foam cell to a small inflammatory cell. Classically, the concept of macrophage …
lipid laden foam cell to a small inflammatory cell. Classically, the concept of macrophage …
Interleukin-10 protects against atherosclerosis by modulating multiple atherogenic macrophage function
X Han, WA Boisvert - Thrombosis and haemostasis, 2015 - thieme-connect.com
Atherosclerosis is primarily a disorder of lipid metabolism, but there is also a prominent
chronic inflammatory component that drives the atherosclerotic lesion progression in the …
chronic inflammatory component that drives the atherosclerotic lesion progression in the …
CD36: implications in cardiovascular disease
M Febbraio, RL Silverstein - The international journal of biochemistry & cell …, 2007 - Elsevier
CD36 is a broadly expressed membrane glycoprotein that acts as a facilitator of fatty acid
uptake, a signaling molecule, and a receptor for a wide range of ligands, including apoptotic …
uptake, a signaling molecule, and a receptor for a wide range of ligands, including apoptotic …
Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages
Roles of ATP binding cassette transporters A1 and G1, scaven... : Current Opinion in Lipidology
Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane …
Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane …