• The clinical use of antipsychotic agents may be enhanced by considering their dose-effect
characteristics. In particular, assessment of immediate and later follow-up treatment of …

The thrust of development of new antipsychotic drugs has been to identify new compounds
that have enhanced antipsychotic efficacy and have lesser side-effects than standard …

Objective: Withdrawal of bipolar mood disorder (BP-I) patients from prolonged, stable lithium
maintenance has a high risk of early recurrence, particularly of mania. We thus compared …

Objectives: To describe the incidence of tardive dyskinesia (TD) in the Yale TD Study and to
identify demographic, treatment, and clinical risk factors for TD occurrence. Design: An …

Despite the large number of elderly patients in nursing homes and the intensity of
medication use there, few current data are available on patterns of medication use in this …

• Initial prophylaxis with anticholinergics for neurolepticinduced extrapyramidal syndromes
(EPSs) is controversial. Recommendations, based on conflicting research findings, vary from …

To relieve confusion about the clinical correlates and prognostic implications of the
dexamethasone suppression test (DST) in schizophrenia, we conducted a DST in 44 …

Duloxetine is a dual inhibitor of norepinephrine (NE) and serotonin (5-HT) uptake. Initial
trials conducted in depressed patients using regimens of 20 mg/day or less did not …

The present study was conducted to establish the degree of interrelationship between
neuropsychological functioning in the acute phase of the schizophrenic illness, clinical …

Tricyclic antidepressants (TCAs) have had a substantial role in the pharmacotherapy of
children and adolescents over the past three decades. Their efficacy has been established …