Traumatic brain injury as a chronic disease: insights from the United States traumatic brain injury model systems research program

K Dams-O'Connor, SB Juengst, J Bogner… - The Lancet …, 2023 - thelancet.com
Traumatic brain injury (TBI) is a global health priority, associated with substantial burden.
Historically conceptualised as an injury event with finite recovery, TBI is now recognised as …

Post-concussion syndrome and chronic traumatic encephalopathy: narrative review on the neuropathology, neuroimaging and fluid biomarkers

I Mavroudis, D Kazis, R Chowdhury, F Petridis, V Costa… - Diagnostics, 2022 - mdpi.com
Traumatic brain injury is a significant public health issue and represents the main contributor
to death and disability globally among all trauma-related injuries. Martial arts practitioners …

Association of traumatic brain injury with the risk of developing chronic cardiovascular, endocrine, neurological, and psychiatric disorders

S Izzy, PM Chen, Z Tahir, R Grashow… - JAMA network …, 2022 - jamanetwork.com
Importance Increased risk of neurological and psychiatric conditions after traumatic brain
injury (TBI) is well-defined. However, cardiovascular and endocrine comorbidity risk after TBI …

[HTML][HTML] INCOG 2.0 guidelines for cognitive rehabilitation following traumatic brain injury, part IV: cognitive-communication and social cognition disorders

L Togher, J Douglas, LS Turkstra… - The Journal of head …, 2023 - journals.lww.com
Methods: An expert panel of clinicians/researchers reviewed evidence published since 2014
and developed updated recommendations for interventions for cognitive-communication …

Post-traumatic epilepsy and comorbidities: advanced models, molecular mechanisms, biomarkers, and novel therapeutic interventions

VM Golub, DS Reddy - Pharmacological reviews, 2022 - ASPET
Post-traumatic epilepsy (PTE) is one of the most devastating long-term, network
consequences of traumatic brain injury (TBI). There is currently no approved treatment that …

Long-term risk of cardiovascular disease after traumatic brain injury: screening and prevention

S Izzy, R Grashow, F Radmanesh, P Chen… - The Lancet …, 2023 - thelancet.com
Traumatic brain injury (TBI) is highly prevalent among individuals participating in contact
sports, military personnel, and in the general population. Although it is well known that brain …

The putative role of neuroinflammation in the interaction between traumatic brain injuries, sleep, pain and other neuropsychiatric outcomes: a state-of-the-art review

A Herrero Babiloni, AA Baril… - Journal of clinical …, 2023 - mdpi.com
Sleep disturbances are widely prevalent following a traumatic brain injury (TBI) and have the
potential to contribute to numerous post-traumatic physiological, psychological, and …

Characterization and treatment of chronic pain after traumatic brain injury—comparison of characteristics between individuals with current pain, past pain, and no pain …

C Harrison-Felix, M Sevigny, CL Beaulieu… - The Journal of Head …, 2024 - journals.lww.com
Objective: To estimate the prevalence of chronic pain after traumatic brain injury (TBI) and
identify characteristics that differ from those without chronic pain. Setting: Community …

Functional and transcriptional profiling of microglial activation during the chronic phase of TBI identifies an age-related driver of poor outcome in old mice

RM Ritzel, Y Li, Z Lei, J Carter, J He, HMC Choi… - Geroscience, 2022 - Springer
Elderly patients with traumatic brain injury (TBI) have greater mortality and poorer outcomes
than younger individuals. The extent to which old age alters long-term recovery and chronic …

Concussion and risk of chronic medical and behavioral health comorbidities

S Izzy, Z Tahir, R Grashow, DJ Cote… - Journal of …, 2021 - liebertpub.com
While chronic neurological effects from concussion have been studied widely, little is known
about possible links between concussion and long-term medical and behavioral …