Enterohepatic circulation: physiological, pharmacokinetic and clinical implications

MS Roberts, BM Magnusson, FJ Burczynski… - Clinical …, 2002 - Springer
Enterohepatic recycling occurs by biliary excretion and intestinal reabsorption of a solute,
sometimes with hepatic conjugation and intestinal deconjugation. Cycling is often …

The emerging functions and mechanisms of mammalian fatty acid–binding proteins

J Storch, B Corsico - Annu. Rev. Nutr., 2008 - annualreviews.org
Fatty acid–binding proteins (FABPs) are abundant intracellular proteins that bind long-chain
fatty acids with high affinity. Nine separate mammalian FABPs have been identified, and …

The fatty acid transport function of fatty acid-binding proteins

J Storch, AEA Thumser - Biochimica et Biophysica Acta (BBA)-Molecular …, 2000 - Elsevier
The intracellular fatty acid-binding proteins (FABPs) comprise a family of 14–15 kDa proteins
which bind long-chain fatty acids. A role for FABPs in fatty acid transport has been …

Identification of intracellular carriers for the endocannabinoid anandamide

M Kaczocha, ST Glaser… - Proceedings of the …, 2009 - National Acad Sciences
The endocannabinoid anandamide (arachidonoyl ethanolamide, AEA) is an uncharged
neuromodulatory lipid that, similar to many neurotransmitters, is inactivated through its …

Cellular uptake and intracellular trafficking of long chain fatty acids

MJ McArthur, BP Atshaves, A Frolov, WD Foxworth… - Journal of lipid …, 1999 - ASBMB
While aspects of cellular fatty acid uptake have been studied as early as 50 years ago,
recent developments in this rapidly evolving field have yielded new functional insights on …

Liver fatty acid-binding protein and obesity

BP Atshaves, GG Martin, HA Hostetler… - The Journal of nutritional …, 2010 - Elsevier
While low levels of unesterified long chain fatty acids (LCFAs) are normal metabolic
intermediates of dietary and endogenous fat, LCFAs are also potent regulators of key …

Cytoplasmic fatty acid-binding proteins: their structure and genes

JH Veerkamp, RGHJ Maatman - Progress in lipid research, 1995 - Elsevier
Lipid-binding,-transfer or-exchange proteins are present in intra-and extracellular fluids of all
organisms. They play a role in the transport or targeting of lipids in the cell or in the plasma …

Role of fatty acid binding proteins and long chain fatty acids in modulating nuclear receptors and gene transcription

F Schroeder, AD Petrescu, H Huang, BP Atshaves… - Lipids, 2008 - Springer
Abnormal energy regulation may significantly contribute to the pathogenesis of obesity,
diabetes mellitus, cardiovascular disease, and cancer. For rapid control of energy …

Starving neurons show sex difference in autophagy

L Du, RW Hickey, H Bayir, SC Watkins… - Journal of Biological …, 2009 - ASBMB
Sex-dependent differences in adaptation to famine have long been appreciated, thought to
hinge on female versus male preferences for fat versus protein sources, respectively …

Fatty acid transfer from liver and intestinal fatty acid-binding proteins to membranes occurs by different mechanisms

KT Hsu, J Storch - Journal of Biological Chemistry, 1996 - ASBMB
Intestinal absorptive cells contain high levels of expression of two homologous fatty acid-
binding proteins (FABP), liver FABP (L-FABP), and intestinal FABP (I-FABP). Both bind long …