The CB1 cannabinoid receptor antagonist rimonabant chronically prevents the nicotine-induced relapse to alcohol
JA López-Moreno, G González-Cuevas… - Neurobiology of …, 2007 - Elsevier
Preclinical and clinical research shows that the cannabinoid brain receptor type 1 (CB1)
modulates alcohol-and nicotine-related behaviors. Throughout the nicotine-induced relapse …
modulates alcohol-and nicotine-related behaviors. Throughout the nicotine-induced relapse …
Effects of CB1 cannabinoid receptor blockade on ethanol preference after chronic alcohol administration combined with repeated re-exposures and withdrawals
F Lallemand, P Soubrie, P De Witte - Alcohol and Alcoholism, 2004 - academic.oup.com
Aims: The cannabinoid CB1 receptor antagonist, SR141716A, differentially affects the
ethanol preference of chronically alcoholized rats when administered during cycles of …
ethanol preference of chronically alcoholized rats when administered during cycles of …
[PDF][PDF] In vivo effects of CB~ 1 receptor ligands on lipid peroxidation and antioxidant defense systems in the brain of healthy and ethanol-treated rats
E Tsvetanova, M Kessiova, A Alexandrova… - Pharmacological …, 2006 - Citeseer
In vivo experiments were conducted to study the effects of N-(piperidin-l-yl)-5-(4-
chlorophenyl)-1-(2, 4-cochlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A; …
chlorophenyl)-1-(2, 4-cochlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A; …
Functional genomics strategies to identify susceptibility genes and treatment targets in alcohol dependence
Genetic factors contribute to alcohol dependence through two main categories of
mechanisms. The 50–60% heritability observed in this disorder is presumably conferred by …
mechanisms. The 50–60% heritability observed in this disorder is presumably conferred by …
Region-specific gene expression changes associated to oleoylethanolamide-induced attenuation of alcohol self-administration
M Gonzalez-Portilla, S Montagud-Romero, S Mellado… - bioRxiv, 2023 - biorxiv.org
Oleoylethanolamide (OEA) is a lipid with anti-inflammatory activity that modulates multiple
reward-related behaviors. Previous studies have shown that OEA treatment reduces alcohol …
reward-related behaviors. Previous studies have shown that OEA treatment reduces alcohol …
[HTML][HTML] JZL184 increases anxiety-like behavior and does not reduce alcohol consumption in female rats after repeated mild traumatic brain injury
Alcohol use disorder (AUD) is highly comorbid with traumatic brain injury (TBI). Previously,
using a lateral fluid percussion model (LFP)(an open model of head injury) to generate a …
using a lateral fluid percussion model (LFP)(an open model of head injury) to generate a …
COX‐2 Inhibition Antagonizes Intra‐Accumbens 2‐Arachidonoylglycerol–Mediated Reduction in Ethanol Self‐Administration in Rats
FJ Pavon, I Polis, DG Stouffer… - Alcoholism: Clinical …, 2020 - Wiley Online Library
Background Ethanol (EtOH) self‐administration is particularly sensitive to the modulation of
CB1 signaling in the nucleus accumbens (NAc) shell, and EtOH consumption increases …
CB1 signaling in the nucleus accumbens (NAc) shell, and EtOH consumption increases …
Adicción y sistema cannabinoide endógeno: papel del receptor para cannabinoides CB1 en la fisiología de las neuronas dopaminérgicas mesotelencefálicas
FR de Fonseca, M Navarro - Adicciones, 2000 - adicciones.es
El sistema cannabinoide endogeno es un nuevo sistema de comunicación intercelular
compuesto por los receptores para cannabinoides CB-1 y CB-2 y varios transmisores …
compuesto por los receptores para cannabinoides CB-1 y CB-2 y varios transmisores …
Are sweetened drinks a gateway to alcohol, opiate and stimulant addiction? Summary of evidence and therapeutic strategies
PN de Silva - Medical Hypotheses, 2020 - Elsevier
Drinks sweetened with both sugar and artificial additives lead to dopamine release at the
nucleus accumbens (NAc) in rat models; the basis of experiences of pleasure in humans …
nucleus accumbens (NAc) in rat models; the basis of experiences of pleasure in humans …
[PDF][PDF] Rola układu kannabinoidowego w patogenezie oraz poszukiwaniu nowych możliwości farmakoterapii zespołu zależności alkoholowej.
B Pietrzak, A Dunaj, K Piątkowska - Advances in Hygiene & …, 2011 - wolnekonopie.org
Brak zadowalającej skuteczności terapii zespołu zależności alkoholowej (ZZA) wciąż
wyznacza nowe kierunki badań. W ostatnim okresie koncentrują się one na transmisji …
wyznacza nowe kierunki badań. W ostatnim okresie koncentrują się one na transmisji …