Hallmarks of HPV carcinogenesis: The role of E6, E7 and E5 oncoproteins in cellular malignancy

D Estêvão, NR Costa, RMG da Costa… - Biochimica et Biophysica …, 2019 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted infectious agent
worldwide, being also responsible for 5% of all human cancers. The integration and …

Peptide-based nanovaccines in the treatment of cervical cancer: a review of recent advances

J Zhang, J Fan, M Skwarczynski… - International Journal …, 2022 - Taylor & Francis
Persistent infection with high-risk human papillomaviruses (HPVs), such as HPV-16 and
HPV-18, can induce cervical cancer in humans. The disease carries high morbidity and …

[HTML][HTML] Molecular landscape of vulvovaginal squamous cell carcinoma: new insights into molecular mechanisms of HPV-associated and HPV-independent …

AM Salama, A Momeni-Boroujeni, C Vanderbilt… - Modern Pathology, 2022 - Elsevier
Squamous cell carcinomas of the lower female genital tract may be human papillomavirus-
associated or independent. We studied the HPV status, mutational repertoire, histology, and …

Epigenetic and genetic keys to fight hpv-related cancers

V Folliero, F Dell'Annunziata, A Chianese, MV Morone… - Cancers, 2023 - mdpi.com
Simple Summary Human papillomavirus (HPV) infection is a highly prevalent sexually
transmitted disease globally. Although most HPV infections do not result in cancer, certain …

The Role of p16/Ki-67 immunostaining, hTERC amplification and fibronectin in predicting cervical cancer progression: a systematic review

ST Voidăzan, C Dianzani, MA Husariu, B Geréd… - Biology, 2022 - mdpi.com
Simple Summary Human papillomaviruses (HPV) are common sexually transmitted
infections and they are responsible for cervical cancer (CC), as well as for several other …

The molecular interplay between human oncoviruses and telomerase in cancer development

ML Tornesello, A Cerasuolo, N Starita, AL Tornesello… - Cancers, 2022 - mdpi.com
Simple Summary The expression of the telomerase reverse transcriptase (TERT) gene is
commonly repressed in terminally differentiated somatic cells and becomes reactivated in …

Epidemiological assessment of oral cancer burden in Pakistan

N Malkani, S Kazmi, MU Rashid - Cancer Investigation, 2021 - Taylor & Francis
Oral cancer ranks first among males and is the primary cause of cancer-related deaths in
Pakistan. We studied the epidemiology and risk factors associated with this cancer. The …

[HTML][HTML] In silico analyzing the molecular interactions of plant-derived inhibitors against E6AP, p53, and c-Myc binding sites of HPV type 16 E6 oncoprotein

F Nabati, M Moradi, H Mohabatkar - Molecular Biology Research …, 2020 - ncbi.nlm.nih.gov
Human papillomaviruses (HPV) are a group of strong human carcinogen viruses considered
to be the fourth leading cause of mortality among women in the world. HPV is the most …

Overexpression of the telomerase holoenzyme induces EMT and tumorigenesis of HPV‐immortalized keratinocytes

A Wang, D Zhou, E Krawczyk, T Li… - Journal of Medical …, 2023 - Wiley Online Library
Cervical cancer is the most frequent malignancy of the female genital tract and is associated
with persistent infection of the uterine cervix with high‐risk human papillomaviruses (HPV) …

TOP2A/MCM2, p16INK4a, and cyclin E1 expression in liquid-based cytology: a biomarkers panel for progression risk of cervical premalignant lesions

O Del Moral-Hernández, D Hernández-Sotelo… - BMC cancer, 2021 - Springer
Background To improve the efficiency of early diagnosis systems for cervical cancer, the use
of cellular and viral markers for identifying precancerous lesions with a greater probability to …