[HTML][HTML] The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum
W Wang, Z Wang, X Yang, Y Gao, X Zhang, L Cao… - Cell discovery, 2021 - nature.com
Dear Editor, Pregnancy-associated malaria (PAM) threatened more than one million women
and their infants in endemic regions in 2019. This resulted in maternal anemia, stillbirth, and …
and their infants in endemic regions in 2019. This resulted in maternal anemia, stillbirth, and …
Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants
L Barfod, T Dobrilovic, P Magistrado… - The Journal of …, 2010 - journals.aai.org
Acquired protection from Plasmodium falciparum placental malaria, a major cause of
maternal, fetal, and infant morbidity, is mediated by IgG specific for the P. falciparum …
maternal, fetal, and infant morbidity, is mediated by IgG specific for the P. falciparum …
[HTML][HTML] The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility
Placental malaria infection is mediated by the binding of the malarial VAR2CSA protein to
the placental glycosaminoglycan, chondroitin sulfate. Recombinant subfragments of …
the placental glycosaminoglycan, chondroitin sulfate. Recombinant subfragments of …
Structure of a Plasmodium falciparum PfEMP1 rosetting domain reveals a role for the N-terminal segment in heparin-mediated rosette inhibition
A Juillerat, A Lewit-Bentley… - Proceedings of the …, 2011 - National Acad Sciences
The human malaria parasite Plasmodium falciparum can cause infected red blood cells
(iRBC) to form rosettes with uninfected RBC, a phenotype associated with severe malaria …
(iRBC) to form rosettes with uninfected RBC, a phenotype associated with severe malaria …
Of mice and women: rodent models of placental malaria
Pregnant women are at increased malaria risk. The infections are characterized by placental
accumulation of infected erythrocytes (IEs) with adverse consequences for mother and baby …
accumulation of infected erythrocytes (IEs) with adverse consequences for mother and baby …
First-Trimester Plasmodium falciparum Infections Display a Typical “Placental” Phenotype
J Doritchamou, G Bertin, A Moussiliou… - The Journal of …, 2012 - academic.oup.com
Background. Plasmodium falciparum–infected erythrocytes (IEs) adhere to host cell
receptors, allowing parasites to sequester into deep vascular beds of various organs. This …
receptors, allowing parasites to sequester into deep vascular beds of various organs. This …
[HTML][HTML] Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report
A Chêne, S Houard, MA Nielsen, S Hundt, F D'Alessio… - 2016 - Springer
Placental malaria caused by Plasmodium falciparum infection constitutes a major health
problem manifesting as severe disease and anaemia in the mother, impaired fetal …
problem manifesting as severe disease and anaemia in the mother, impaired fetal …
Pre-clinical and clinical development of the first placental malaria vaccine
C Pehrson, A Salanti, TG Theander… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Malaria during pregnancy is a massive health problem in endemic areas.
Placental malaria infections caused by Plasmodium falciparum are responsible for up to one …
Placental malaria infections caused by Plasmodium falciparum are responsible for up to one …
[HTML][HTML] Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions
S Gangnard, A Lewit-Bentley, S Dechavanne… - Scientific reports, 2015 - nature.com
The human malaria parasite, Plasmodium falciparum, is able to evade spleen-mediated
clearing from blood stream by sequestering in peripheral organs. This is due to the adhesive …
clearing from blood stream by sequestering in peripheral organs. This is due to the adhesive …
[HTML][HTML] Kinetics of B cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Naturally acquired protective immunity to Plasmodium falciparum malaria takes years to
develop. It relies mainly on Abs, particularly IgG specific for Plasmodium falciparum …
develop. It relies mainly on Abs, particularly IgG specific for Plasmodium falciparum …