Extra virgin olive oil (EVOO) consumption reduces the risk of cardiovascular disease in high-
risk groups and the polyphenols in EVOO play an important health effect on it. As one of the …

Polychlorinated biphenyls (PCBs) are persistent organic toxicants derived from legacy
pollution sources and their formation as inadvertent byproducts of some current …

Background & Aims Sulfoconjugation of small molecules or protein peptides is a key
mechanism to ensure biochemical and functional homeostasis in mammals. The PAPS …

Male and female offspring of obese mothers are known to differ extensively in their
metabolic adaptation and later development of complications. We investigate the sex …

Primary biliary cholangitis (PBC) is a rare chronic cholestatic and immune-mediated liver
disease of unknown aetiology that targets intrahepatic bile duct cells (cholangiocytes) and …

Increased disposition of thyroid hormones is a way that xenobiotics may alter thyroid
homeostasis and, in rats, produce thyroid follicular adenoma/carcinoma. This capacity is …

Colchicine is widely used to treat gouty arthritis for years. Previous studies showed that
colchicine overdose can cause liver damage, yet the mechanism underlying its …

Gemfibrozil (GEM), a lipid regulator, is a fibric acid derivative widely used in the treatment of
hyperlipidemia. It has been reported that GEM can induce acute liver injury in the course of …

Glyphosate (GLY) is an herbicide used for rural and urban weed control. Urinary GLY in
women is associated with shortened gestational length yet effects of GLY on offspring due to …

Extensive phase II metabolic reactions (ie, glucuronidation and sulfation) have resulted in
low bioavailability and decreased biological effects of curcumin and quercetin. Compared to …