Developing machine learning algorithms for dynamic estimation of progression during active surveillance for prostate cancer

C Lee, A Light, ES Saveliev, M Van der Schaar… - NPJ digital …, 2022 - nature.com
Active Surveillance (AS) for prostate cancer is a management option that continually
monitors early disease and considers intervention if progression occurs. A robust method to …

Redevelopment of the Predict: Breast Cancer website and recommendations for developing interfaces to support decision‐making

GD Farmer, M Pearson, WJ Skylark… - Cancer …, 2021 - Wiley Online Library
Objectives To develop a new interface for the widely used prognostic breast cancer tool:
Predict: Breast Cancer. To facilitate decision‐making around post‐surgery breast cancer …

Metabolic profiling of thymic epithelial tumors hints to a strong Warburg effect, glutaminolysis and precarious redox homeostasis as potential therapeutic targets

M Alwahsh, R Knitsch, R Marchan, J Lambert… - Cancers, 2022 - mdpi.com
Simple Summary Thymomas and thymic carcinomas (TCs) are malignant thymic epithelial
tumors (TETs) with poor outcome, if non-resectable. Metabolic signatures of TETs have not …

Nomograms to predict the prognosis in locally advanced oral squamous cell carcinoma after curative resection

Z Nie, P Zhao, Y Shang, B Sun - BMC cancer, 2021 - Springer
Background Oral squamous cell carcinoma (OSCC) is the dominant histologic type of oral
cancer. Locally advanced OSCC remains a major therapeutic challenge. Our study aimed to …

Clinical impact of the predict prostate risk communication tool in men newly diagnosed with nonmetastatic prostate cancer: A multicentre randomised controlled trial

D Thurtle, V Jenkins, A Freeman, M Pearson… - European Urology, 2021 - Elsevier
Abstract Background Predict Prostate is a freely available online personalised risk
communication tool for men with nonmetastatic prostate cancer. Its accuracy has been …

Adaption and National Validation of a Tool for Predicting Mortality from Other Causes Among Men with Nonmetastatic Prostate Cancer

AC Justice, JP Tate, F Howland, JM Gaziano… - European Urology …, 2024 - Elsevier
Background An electronic health record–based tool could improve accuracy and eliminate
bias in provider estimation of the risk of death from other causes among men with …

Shifting the paradigm in the management of early prostate cancer

V Gnanapragasam - British Journal of Cancer, 2024 - nature.com
Outcomes from active surveillance have clearly shown that it is the optimal method of
managing many early prostate cancers. Yet, clinician training and healthcare systems are …

Prostate cancer genotyping for risk stratification and precision treatment

AA Kumar - Current Urology, 2024 - journals.lww.com
Prostate cancer (PC) is the most frequently diagnosed cancer and second leading cause of
cancer-related deaths in men. It is heterogeneous, as is evident from the wide spectrum of …

Development and validation of accelerated failure time model for cause-specific survival and prognostication of oral squamous cell carcinoma: SEER data analysis

P Awodutire, M Kattan, OA Akadiri - PloS one, 2024 - journals.plos.org
Background Oral Squamous Cell Carcinoma is the most prevalent malignancies affecting
the oral cavity. Despite progress in studies and treatment options its outlook remains grim …

Comparative performance and external validation of the multivariable PREDICT Prostate tool for non-metastatic prostate cancer: a study in 69,206 men from Prostate …

D Thurtle, O Bratt, P Stattin, P Pharoah… - BMC medicine, 2020 - Springer
Background PREDICT Prostate is an endorsed prognostic model that provides
individualised long-term prostate cancer-specific and overall survival estimates. The model …