The mechanisms by which cells sense their mechanical environment and transduce the
signal through focal adhesions and signaling pathways to the nucleus is an area of key …

The skeletal system, which contains bones, joints, tendons, ligaments and other elements,
plays a wide variety of roles in body shaping, support and movement, protection of internal …

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase and distributes important
regulatory functions in skeletal system. Mesenchymal stem cell (MSC) possesses significant …

How cells move is a fundamental biological question. The directionality of adherent
migrating cells depends on the assembly and disassembly (turnover) of focal adhesions …

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase over-expressed and
activated in both adult and pediatric cancers, where it plays important roles in the regulation …

Focal adhesions are specialized integrin-dependent adhesion complexes, which ensure cell
anchoring to the extracellular matrix. Focal adhesions also function as mechano-signaling …

Simple Summary The importance of stem cells for regenerative medicine has grown
significantly in recent years. This is because stem cells can differentiate into multiple cell …

Simple Summary Neurons are biological wires that send signals not only across the brain,
but throughout the body. Like almost all cells in the human body, neurons adhere to their …

The complex interplay between cells and materials is a key focus of this research, aiming to
develop optimal scaffolds for regenerative medicine. The need for tissue regeneration …

Mechanical stimulation is an effective approach for controlling stem cell differentiation in
tissue engineering. However, its realization in in vivo tissue repair remains challenging …