Główny mechanizm działania niesteroidowych leków przeciwzapalnych (NLPZ) polega na
zahamowaniu syntezy prostaglandyn [1] przez blokowanie aktywności izoform enzymu …

O Celecoxib, antiinflamatório não esteroidal, inibidor seletivo da COX-2, tem se mostrado
um importante agente anticarcinogênico, mas o seu papel no carcinoma epidermóide de …

The arachidonic acid–prostaglandin pathway has been implicated in many types of
malignancies. NSAIDs can inhibit prostaglandin production but concerns about the potential …

Diversas alterações genéticas estão associadas à patogênese do carcinoma epidermoide
(CE), a neoplasia maligna mais comum de cabeça e pescoço. Algumas dessas alterações …

Colorectal cancer (CRC) is the second most common form of cancer in the world and the
most common cancer in Singapore. The limitations of the currently available methods and …

Carcinogenesis has been viewed as an evolutionary process described as “somatic
evolution” as it requires a sequence of genetic changes; however, recent models of …

Breast cancer remains a major health concern, despite efforts to develop improved
therapeutics. Chemoprevention is a promising strategy for reducing breast cancer-related …

Breast cancer remains a major health concern, despite efforts to develop improved
therapeutics. Chemoprevention is a promising strategy for reducing breast cancer-related …

I wish to recognize the support of the Kidney Foundation of canada, the university of
Manitoba, the Manitoba Institute of child Health and the Manitoba Health Research Council …

Introdução: A hipótese mais aceita atualmente na carcinogênese ovariana é a da ovulação
incessante. O traumatismo causado pela ruptura do folículo ovulatório no epitélio ovariano …