Integration of GC–MS and LC–MS for untargeted metabolomics profiling
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …
scientific community as it is applied in several researches relating to diseases diagnosis …
Environmental metabolomics: an emerging approach to study organism responses to environmental stressors
BP Lankadurai, EG Nagato… - Environmental …, 2013 - cdnsciencepub.com
Metabolomics is the analysis of endogenous and exogenous low molecular mass
metabolites within a cell, tissue, or biofluid of an organism in response to an external …
metabolites within a cell, tissue, or biofluid of an organism in response to an external …
[PDF][PDF] The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting α-ketoglutarate to 2-hydroxyglutarate
PS Ward, J Patel, DR Wise, O Abdel-Wahab… - Cancer cell, 2010 - cell.com
The somatic mutations in cytosolic isocitrate dehydrogenase 1 (IDH1) observed in gliomas
can lead to the production of 2-hydroxyglutarate (2HG). Here, we report that tumor 2HG is …
can lead to the production of 2-hydroxyglutarate (2HG). Here, we report that tumor 2HG is …
Metabolomics: a global biochemical approach to drug response and disease
R Kaddurah-Daouk, BS Kristal… - Annu. Rev. Pharmacol …, 2008 - annualreviews.org
Metabolomics is the study of metabolism at the global level. This rapidly developing new
discipline has important potential implications for pharmacologic science. The concept that …
discipline has important potential implications for pharmacologic science. The concept that …
Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks
P Bernini, I Bertini, C Luchinat, P Nincheri… - Journal of biomolecular …, 2011 - Springer
Abstract 1 H NMR metabolic profiling of urine, serum and plasma has been used to monitor
the impact of the pre-analytical steps on the sample quality and stability in order to propose …
the impact of the pre-analytical steps on the sample quality and stability in order to propose …
Metabolomics tools for identifying biomarkers for neuropsychiatric diseases
MP Quinones, R Kaddurah-Daouk - Neurobiology of disease, 2009 - Elsevier
The repertoire of biochemicals (or small molecules) present in cells, tissue, and body fluids
is known as the metabolome. Today, clinicians utilize only a very small part of the …
is known as the metabolome. Today, clinicians utilize only a very small part of the …
[HTML][HTML] Green systems biology—from single genomes, proteomes and metabolomes to ecosystems research and biotechnology
W Weckwerth - Journal of proteomics, 2011 - Elsevier
Plants have shaped our human life form from the outset. With the emerging recognition of
world population feeding, global climate change and limited energy resources with fossil …
world population feeding, global climate change and limited energy resources with fossil …
Metabolomic tools used in marine natural product drug discovery
KA Stuart, K Welsh, MC Walker… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction: The marine environment is a very promising resource for natural product
research, with many of these reaching the market as new drugs, especially in the field of …
research, with many of these reaching the market as new drugs, especially in the field of …
PANOMICS at the interface of root–soil microbiome and BNI
Nitrification and denitrification are soil biological processes responsible for large nitrogen
losses from agricultural soils and generation of the greenhouse gas (GHG) N 2 O. Increased …
losses from agricultural soils and generation of the greenhouse gas (GHG) N 2 O. Increased …
Combined application of NMR-and GC-MS-based metabonomics yields a superior urinary biomarker panel for bipolar disorder
Bipolar disorder (BD) is a debilitating mental disorder that cannot be diagnosed by objective
laboratory-based modalities. Our previous studies have independently used nuclear …
laboratory-based modalities. Our previous studies have independently used nuclear …