Oxygen-tolerant [NiFe] hydrogenases may be used in future photobiological hydrogen
production systems once the enzymes can be heterologously expressed in host organisms …

Bipolar disorder (BD) is a common and debilitating mental disorder. Bipolar depression is
the main episode of BD. Furthermore, there are no objective biomarkers available for …

Metabolomics is an “omic” science that is now emerging with the purpose of elaborating a
comprehensive analysis of the metabolome, which is the complete set of metabolites (ie …

Metabolomics is likely an ideal tool to assess tobacco smoke exposure and the impact of
cigarette smoke on human exposure and health. To assess reproducibility and feasibility of …

Bipolar disorder (BD) is a brain disorder that causes changes in a person's mood, energy,
and ability to function. It has a prevalence of 60 million people worldwide, and it is among …

The circadian clock is a cell-autonomous time-keeping mechanism established gradually
during embryonic development. Here, we generated a transgenic zebrafish line carrying a …

Metabolomics and metabolic flux analysis (MFA) are powerful tools in the arsenal of
methodologies of systems biology. Currently, metabolomics techniques are applied routinely …

Environmental context Metabolomics can be used to provide a snapshot of an organism's
physiology as the organism is exposed to varying environmental conditions. In this study …

Pesticides are being applied at a greater extent than in the past. Once pesticides enter the
ecosystem, many environmental factors can influence their residence time. These …

Endosulfan is an environmentally persistent pesticide and has been shown to be genotoxic,
neurotoxic and carcinogenic to surrounding organisms. Earthworms are widely used in …