Simple Summary The environment surrounding primary glioma brain tumors plays a critical
role in tumor development and progression. Immune cells are important constituents of this …

Simple Summary Despite multi-modal treatment consisting of surgery, chemotherapy, and
radiation, glioblastoma inevitably recurs due to its diffuse infiltrative nature. Anti-tumor …

Glioblastoma (GBM) is the most malignant type of primary intracranial tumor with a median
overall survival of only 14 months, a very poor prognosis and a recurrence rate of 90%. It is …

Oncolytic viruses are multifaceted tumor killers, which can function as tumor vaccines to
boost systemic antitumor immunity. In previous study, we rationally designed a synthetic …

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor,
characterized by high heterogeneity, strong invasiveness, poor prognosis, and a low …

Abstract Background One‐carbon (1C) metabolism is a metabolic network that plays
essential roles in biological reactions. In 1C metabolism, a series of nutrients are used to …

Glioblastoma (GBM) is a highly aggressive tumor with a devastating impact on quality-of-life
and abysmal survivorship. Patients have very limited effective treatment options. The …

Introduction Advanced hepatocellular carcinoma (HCC) represents a significant global
health burden, whose treatment has been recently revolutionized by the advent of biologic …

Breast cancer is a highly heterogeneous disease, at both inter-and intra-tumor levels, and
this heterogeneity is a crucial determinant of malignant progression and response to …

Liver metastases (LMS) commonly arise from gastrointestinal tumors, such as colorectal
cancer (CRC) and pancreatic cancer (PDAC). The immunosuppressive environment of the …