Chronic airway colonisation by Pseudomonas aeruginosa, a hallmark of cystic fibrosis (CF)
lung disease, is associated with increased morbidity and mortality and despite aggressive …

The airways of persons with cystic fibrosis are prone to infection by a diverse and dynamic
polymicrobial consortium. Currently, no models exist that permit recapitulation of this …

Pseudomonas aeruginosa is a facultative pathogen that can cause, inter alia, acute or
chronic pneumonia in predisposed individuals. The gram-negative bacterium displays …

Pseudomonas aeruginosa is a major cause of respiratory biofilm-related infections in
patients with cystic fibrosis. We developed an in vitro pharmacodynamic model to study the …

Cystic fibrosis (CF) disease provokes the accumulation of thick and viscous sputum in the
lungs, favoring the development of chronic and polymicrobial infections. Pseudomonas …

Biofilms are key players in the pathogenesis of most of chronic infections associated with
host tissue or fluids and indwelling medical devices. These chronic infections are hard to be …

Aim: To investigate the role of pre-established Staphylococcus aureus on Pseudomonas
aeruginosa adaptation and antibiotic tolerance. Materials & methods: Bacteria were cultured …

The airways of people with cystic fibrosis (CF) are often chronically colonised with a diverse
array of bacterial and fungal species. However, little is known about the relative partitioning …

Pseudomonas aeruginosa, a ubiquitous opportunistic pathogen, is a leading cause of
chronic infection of airways in cystic fibrosis (CF) patients. Chronic infections typically arise …

The airway mucus of patients with cystic fibrosis has altered properties which create a
microenvironment primed for chronic infections that are difficult to treat. These complex …