Bee venom: an updating review of its bioactive molecules and its health applications
M Carpena, B Nuñez-Estevez, A Soria-Lopez… - Nutrients, 2020 - mdpi.com
Bee venom (BV) is usually associated with pain since, when humans are stung by bees,
local inflammation and even an allergic reaction can be produced. BV has been traditionally …
local inflammation and even an allergic reaction can be produced. BV has been traditionally …
Computational methods and tools in antimicrobial peptide research
PGA Aronica, LM Reid, N Desai, J Li… - Journal of Chemical …, 2021 - ACS Publications
The evolution of antibiotic-resistant bacteria is an ongoing and troubling development that
has increased the number of diseases and infections that risk going untreated. There is an …
has increased the number of diseases and infections that risk going untreated. There is an …
Therapeutic Use of Bee venom and potential applications in veterinary medicine
Simple Summary Bee products consist of many substances that have long been known for
their medicinal and health-beneficial properties. Venom is certainly the one that has …
their medicinal and health-beneficial properties. Venom is certainly the one that has …
How melittin inserts into cell membrane: conformational changes, inter-peptide cooperation, and disturbance on the membrane
J Hong, X Lu, Z Deng, S Xiao, B Yuan, K Yang - Molecules, 2019 - mdpi.com
Antimicrobial peptides (AMPs), as a key component of the immune defense systems of
organisms, are a promising solution to the serious threat of drug-resistant bacteria to public …
organisms, are a promising solution to the serious threat of drug-resistant bacteria to public …
Mechanistic understanding from molecular dynamics in pharmaceutical research 2: lipid membrane in drug design
We review the use of molecular dynamics (MD) simulation as a drug design tool in the
context of the role that the lipid membrane can play in drug action, ie, the interaction …
context of the role that the lipid membrane can play in drug action, ie, the interaction …
Strategies for Improving Transdermal Administration: New Approaches to Controlled Drug Release
O Dumitriu Buzia, AM Păduraru, CS Stefan, M Dinu… - Pharmaceutics, 2023 - mdpi.com
In this work, we aim to address several strategies to improve transdermal drug delivery, such
as iontophoresis, sonophoresis, electroporation and micron. We also propose a review of …
as iontophoresis, sonophoresis, electroporation and micron. We also propose a review of …
Anisaxins, helical antimicrobial peptides from marine parasites, kill resistant bacteria by lipid extraction and membrane disruption
An infecting and propagating parasite relies on its innate defense system to evade the host's
immune response and to survive challenges from commensal bacteria. More so for the …
immune response and to survive challenges from commensal bacteria. More so for the …
Electrochemiluminescence imaging of liposome permeabilization by an antimicrobial peptide: melittin
F Ben Trad, J Delacotte… - … & Biomedical Imaging, 2023 - ACS Publications
The permeabilization of liposomes by melittin, an antimicrobial peptide (AMP), has been
studied by an electrochemiluminescence (ECL) imaging strategy. The methodology …
studied by an electrochemiluminescence (ECL) imaging strategy. The methodology …
The membrane effects of melittin on gastric and colorectal cancer
The cytotoxic effects of melittin, a bee-venom peptide, have been widely studied towards
cancer cells. Typically, these studies have examined the effect of melittin over extended-time …
cancer cells. Typically, these studies have examined the effect of melittin over extended-time …
Cooperative antimicrobial action of melittin on lipid membranes: A coarse-grained molecular dynamics study
Y Miyazaki, W Shinoda - Biochimica et Biophysica Acta (BBA) …, 2022 - Elsevier
We conducted a series of coarse-grained molecular dynamics (CG-MD) simulations to
investigate the complicated actions of melittin, which is an antimicrobial peptide (AMP) …
investigate the complicated actions of melittin, which is an antimicrobial peptide (AMP) …