Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor
in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved …

The expression of ULK1, a core protein of autophagy, is closely related to autophagic
activity. Numerous studies have shown that pathological abnormal expression of ULK1 is …

The PRMT5-MEP50 methyltransferase is a major target for anticancer drug discovery, and
modulators of its interactions with different regulatory proteins are in high demand because …

Plants undergo transcriptome reprograming to adapt to daily and seasonal fluctuations in
light and temperature conditions. While most efforts have focused on the role of master …

The spliceosome, responsible for all mature protein-coding transcripts of eukaryotic intron-
containing genes, consists of small uridine-rich nuclear ribonucleoproteins (UsnRNPs). The …

The survival motor neuron (SMN) complex is a multi-megadalton complex involved in post-
transcriptional gene expression in eukaryotes via promotion of the biogenesis of uridine-rich …

Alterations in the spliceosome pathway (SP) have been associated with diverse human
cancers. In this study, we explored associations of the SP activity with various clinical …

Protein-arginine methylation is a common posttranslational modification, crucial to various
cellular processes, such as protein-protein interactions or binding to nucleic acids. The …

Plants undergo transcriptome reprogramming to adapt to daily and seasonal fluctuations in
light and temperature conditions. While most efforts have focused on the role of master …

Triple negative breast cancer (TNBC) is an aggressive tumor characterized by high inter-and
intra-tumoral heterogeneity, enrichment in breast cancer stem cells, resistance to treatment …