Recommendations for (discontinuation of) statin treatment in older adults: review of guidelines

MA van der Ploeg, C Floriani… - Journal of the …, 2020 - Wiley Online Library
OBJECTIVES As a person's age increases and his/her health status declines, new
challenges arise that may lead physicians to consider deprescribing statins. We aimed to …

Lipid-modifying therapy in the elderly

I Hamilton-Craig, D Colquhoun, K Kostner… - Vascular Health and …, 2015 - Taylor & Francis
Cardiovascular disease (CVD) mortality and morbidity increases with increasing age, largely
as a result of increased lifetime exposure as well as increased prevalence of CVD risk …

Statin prescribing according to gender, age and indication: what about the benefit–risk balance?

H Wallach‐Kildemoes, H Stovring… - Journal of evaluation …, 2016 - Wiley Online Library
Rationales, aims and objectives The increasing dispensing of statins has raised concern
about the appropriateness of prescribing to various population groups. We aimed to (1) …

How common is statin use in the oldest old?

W Thompson, A Pottegård, JB Nielsen, P Haastrup… - Drugs & Aging, 2018 - Springer
There is a lack of evidence surrounding the efficacy of statins in the oldest old (≥ 80 years of
age). As such, there is controversy surrounding use of statins in this population. We sought …

Patient characteristics and general practitioners' advice to stop statins in oldest-old patients: a survey study across 30 countries

MA van der Ploeg, S Streit, WP Achterberg… - Journal of general …, 2019 - Springer
Background Statins are widely used to prevent cardiovascular disease (CVD). With
advancing age, the risks of statins might outweigh the potential benefits. It is unclear which …

Statin combined with exercise training is more effective to improve functional status in dyslipidemic older adults

LC Baptista, MT Veríssimo… - Scandinavian Journal of …, 2018 - Wiley Online Library
Background Exercise training (EX) and statins are first‐line therapies to manage
dyslipidemia. Purpose This study aims to analyze the effect of EX and statins on functional …

Statins in older Danes: factors associated with discontinuation over the first 4 years of use

W Thompson, DE Jarbøl, P Haastrup… - Journal of the …, 2019 - Wiley Online Library
BACKGROUND AND OBJECTIVE Use of statins is considerable among older persons. We
investigated factors associated with statin discontinuation in new statin users aged 70 years …

Changes in statin prescription patterns in patients admitted to an Australian geriatric subacute unit

S Noaman, O Al-Mukhtar, S Abramovic… - Heart, Lung and …, 2019 - Elsevier
Background Assessment of demographic and clinical factors influencing the decision of
statin discontinuation in the elderly population admitted to subacute geriatric unit. The aim of …

Countdown to a silver jubilee for Heart, Lung and Circulation Journal in 2016–Looking back in order to move forward

AR Denniss, AT Gregory - Heart, Lung and Circulation, 2015 - heartlungcirc.org
Conclusions Other topics have been covered over the last two years, including many areas
of newer techniques of imaging, as well as basic research, which will be addressed in …

A population-based study of cholesterol measurements in the oldest old

C Gils, K Christensen, M Nybo - Current Aging Science, 2015 - ingentaconnect.com
Background: Effect of lipid-lowering treatment in the oldest old is a matter of debate as there
is no unequivocal evidence of statins being beneficial among the oldest. The need for …