Cerebral vascular disease and neurovascular injury in ischemic stroke

X Hu, TM De Silva, J Chen, FM Faraci - Circulation research, 2017 - Am Heart Assoc
The consequences of cerebrovascular disease are among the leading health issues
worldwide. Large and small cerebral vessel disease can trigger stroke and contribute to the …

Pathophysiology and therapy of experimental stroke

KA Hossmann - Cellular and molecular neurobiology, 2006 - Springer
1. Stroke is the neurological evidence of a critical reduction of cerebral blood flow in a
circumscribed part of the brain, resulting from the sudden or gradually progressing …

Variability of cerebral blood volume and oxygen extraction: stages of cerebral haemodynamic impairment revisited

CP Derdeyn, TO Videen, KD Yundt, SM Fritsch… - Brain, 2002 - academic.oup.com
The presence or degree of haemodynamic impairment due to occlusive cerebrovascular
disease is often inferred from measurements of cerebral blood flow (CBF), cerebral blood …

Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathways

JH Yon, J Daniel-Johnson, LB Carter… - Neuroscience, 2005 - Elsevier
It was shown recently that exposure of the developing rat brain during the peak of
synaptogenesis to commonly used general anesthetics can trigger widespread apoptotic …

Relationship between hypotension and cerebral ischemia during hemodialysis

C MacEwen, S Sutherland, J Daly, C Pugh… - Journal of the …, 2017 - journals.lww.com
The relationship between BP and downstream ischemia during hemodialysis has not been
characterized. We studied the dynamic relationship between BP, real-time symptoms, and …

Ischaemic brain oedema

C Ayata, AH Ropper - Journal of Clinical Neuroscience, 2002 - Elsevier
Ischaemic brain oedema appears to involve two distinct processes, the relative contribution
and time course of which depend on the duration and severity of ischaemia, and the …

Effects of hypervolemia and hypertension on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation after subarachnoid hemorrhage

E Muench, P Horn, C Bauhuf, H Roth… - Critical care …, 2007 - journals.lww.com
Objective: Hypertensive, hypervolemic, hemodilution therapy (triple-H therapy) is a generally
accepted treatment for cerebral vasospasm after subarachnoid hemorrhage. However, the …

Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage

WJ Powers, AR Zazulia, TO Videen, RE Adams… - Neurology, 2001 - AAN Enterprises
Background: Arterial hypertension is common in the first 24 hours after acute intracerebral
hemorrhage (ICH). Although increased blood pressure usually declines to baseline values …

Acute hypertension after stroke: the scientific basis for treatment decisions

WJ Powers - Neurology, 1993 - AAN Enterprises
Arterial hypertension is one of the most potent risk factors for stroke. Controlled clinical trials
have consistently demonstrated that prolonged pharmacologic reduction in blood pressure …

The acetazolamide challenge: techniques and applications in the evaluation of chronic cerebral ischemia

AS Vagal, JL Leach… - American journal of …, 2009 - Am Soc Neuroradiology
The acetazolamide (ACZ) challenge test is a useful clinical tool and a reliable predictor of
critically reduced perfusion. In patients with chronic steno-occlusive disease, the ability to …