Intracerebral hemorrhage (ICH) is the second most common type of stroke and has one of
the highest fatality rates of any disease. There are many clinical signs and symptoms after …

The neurotrophin family of neurotrophic factors are well-known for their effects on neuronal
survival and growth. Over the past decade, considerable evidence has accumulated from …

Neurotrophins (NTs) belong to a family of trophic factors that regulate the survival, growth
and programmed cell death of neurons. In mammals, there are four structurally and …

At least some neurotrophins may be powerful modulators of synapses, thereby influencing
short-and long-term synaptic efficiency. BDNF acts at central synapses in pain pathways …

Introduction: Central sensitization is a form of maladaptive neuroplasticity underlying many
chronic pain disorders, including neuropathic pain, fibromyalgia, whiplash, headache …

Neural stem cells are a self-renewing population that generates the neurons and glia of the
developing brain. They can be isolated, proliferated, genetically manipulated and …

Brain-derived neurotrophic factor (BDNF) is synthesized by small neuron cell bodies in the
dorsal root ganglia (DRG) and is anterogradely transported to primary afferent terminals in …

Neurotrophic factors, which support neuronal survival and growth during development of the
nervous system, have been shown to play significant roles in the transmission of physiologic …

Chronic pain is sustained, in part, through the intricate process of central sensitization (CS),
marked by maladaptive neuroplasticity and neuronal hyperexcitability within central pain …

Orofacial pain represents a multidisciplinary biomedical challenge involving basic and
clinical research for which no satisfactory solution has been found. In this regard, trigeminal …