A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …

Antiviral effect of phytochemicals from medicinal plants: Applications and drug delivery strategies

S Ben-Shabat, L Yarmolinsky, D Porat… - Drug delivery and …, 2020 - Springer
Viral infections affect three to five million patients annually. While commonly used antivirals
often show limited efficacy and serious adverse effects, herbal extracts have been in use for …

Ursolic and oleanolic acids: Plant metabolites with neuroprotective potential

E Gudoityte, O Arandarcikaite, I Mazeikiene… - International Journal of …, 2021 - mdpi.com
Ursolic and oleanolic acids are secondary plant metabolites that are known to be involved in
the plant defence system against water loss and pathogens. Nowadays these triterpenoids …

Self-nanoemulsifying drug delivery systems: formulation insights, applications and advances

AA Date, N Desai, R Dixit, M Nagarsenker - Nanomedicine, 2010 - Future Medicine
There has been a resurgence of interest in nanoemulsions for various pharmaceutical
applications since low-energy emulsification methods, such as spontaneous or self …

Pentacyclic triterpene distribution in various plants–rich sources for a new group of multi-potent plant extracts

S Jäger, H Trojan, T Kopp, MN Laszczyk, A Scheffler - Molecules, 2009 - mdpi.com
Pentacyclic triterpenes are secondary plant metabolites widespread in fruit peel, leaves and
stem bark. In particular the lupane-, oleanane-, and ursane triterpenes display various …

Self-microemulsifying drug delivery system (SMEDDS)–challenges and road ahead

S Dokania, AK Joshi - Drug delivery, 2015 - Taylor & Francis
Self-microemulsifying drug delivery system (SMEDDS) has emerged as a vital strategy to
formulate poor water soluble compounds for bioavailability enhancement. However, certain …

Structural diversity, fermentation production, bioactivities and applications of triterpenoids from several common medicinal fungi: Recent advances and future …

P Zhao, M Guan, W Tang, N Walayat, Y Ding, J Liu - Fitoterapia, 2023 - Elsevier
Medicinal fungi are beneficial to human health and it reduces the risk of chronic diseases.
Triterpenoids are polycyclic compounds derived from the straight-chain hydrocarbon …

Nanoemulsion loaded polymeric hydrogel for topical delivery of curcumin in psoriasis

MS Algahtani, MZ Ahmad, J Ahmad - Journal of Drug Delivery Science and …, 2020 - Elsevier
Curcumin is a natural compound with multiple molecular targets that causes inhibition of
factors involved in pathogenesis of psoriasis but low solubility and poor skin penetrability …

Pentacyclic triterpene bioavailability: An overview of in vitro and in vivo studies

NA JC Furtado, L Pirson, H Edelberg, L M. Miranda… - Molecules, 2017 - mdpi.com
Pentacyclic triterpenes are naturally found in a great variety of fruits, vegetables and
medicinal plants and are therefore part of the human diet. The beneficial health effects of …

Curcumin-loaded solid lipid nanoparticles have prolonged in vitro antitumour activity, cellular uptake and improved in vivo bioavailability

J Sun, C Bi, HM Chan, S Sun, Q Zhang… - Colloids and surfaces b …, 2013 - Elsevier
Purpose The aim of the present study was to blend liquid lipids with solid lipids to
encapsulate curcumin in solid lipid nanoparticles (SLNs), thereby improving the …