Central regulation of stress-evoked peripheral immune responses

KL Chan, WC Poller, FK Swirski… - Nature Reviews …, 2023 - nature.com
Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

Glucocorticoid therapy in inflammatory bowel disease: mechanisms and clinical practice

S Bruscoli, M Febo, C Riccardi, G Migliorati - Frontiers in immunology, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn's disease
(CD). IBD etiopathology is multifactorial and involves alteration of immune cells and chronic …

The immune checkpoint PD-1 in natural killer cells: expression, function and targeting in tumour immunotherapy

L Quatrini, FR Mariotti, E Munari, N Tumino, P Vacca… - Cancers, 2020 - mdpi.com
Simple Summary Natural killer cells are innate cytotoxic lymphocytes that play a key role in
the anti-tumor immune response. In the tumor microenvironment, however, the effector …

Postoperative systemic inflammatory dysregulation and corticosteroids: a narrative review

CR Bain, PS Myles, T Corcoran, JM Dieleman - Anaesthesia, 2023 - Wiley Online Library
In some patients, the inflammatory‐immune response to surgical injury progresses to a
harmful, dysregulated state. We posit that postoperative systemic inflammatory dysregulation …

Mechanisms of action and efficacy of hyaluronic acid, corticosteroids and platelet-rich plasma in the treatment of temporomandibular joint osteoarthritis—a systematic …

M Derwich, M Mitus-Kenig, E Pawlowska - International journal of …, 2021 - mdpi.com
Temporomandibular joint osteoarthritis (TMJ OA) is a low-inflammatory disorder with
multifactorial etiology. The aim of this review was to present the current state of knowledge …

Potential role of antioxidant and anti-inflammatory therapies to prevent severe SARS-Cov-2 complications

AM Fratta Pasini, C Stranieri, L Cominacini, C Mozzini - Antioxidants, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel severe acute
respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2). Here, we review the …

Glucocorticoid resistance: interference between the glucocorticoid receptor and the MAPK signalling pathways

LM Sevilla, A Jiménez-Panizo, A Alegre-Martí… - International Journal of …, 2021 - mdpi.com
Endogenous glucocorticoids (GCs) are steroid hormones that signal in virtually all cell types
to modulate tissue homeostasis throughout life. Also, synthetic GC derivatives …

Glucocorticoids increase adiposity by stimulating Krüppel-like factor 9 expression in macrophages

Y Zhang, C Du, W Wang, W Qiao, Y Li, Y Zhang… - Nature …, 2024 - nature.com
The mechanisms underlying glucocorticoid (GC)-induced obesity are poorly understood.
Macrophages are the primary targets by which GCs exert pharmacological effects and …

The impact of obesity on microglial function: Immune, metabolic and endocrine perspectives

VI Alexaki - Cells, 2021 - mdpi.com
Increased life expectancy in combination with modern life style and high prevalence of
obesity are important risk factors for development of neurodegenerative diseases …

[HTML][HTML] The Role of Glucocorticoids in the Management of COVID-19

VI Alexaki, H Henneicke - Hormone and Metabolic Research, 2021 - thieme-connect.com
Coronavirus disease 2019 (COVID-19), caused by an infection with the novel coronavirus
SARS-CoV-2, has resulted in a global pandemic and poses an emergency to public health …