More than 80 mutant mouse genes disrupt neurulation and allow an in-depth analysis of the
underlying developmental mechanisms. Although many of the genetic mutants have been …

Fumonisins are a family of toxic and carcinogenic mycotoxins produced by Fusarium
verticillioides (formerly Fusarium moniliforme), a common fungal contaminant of maize …

Neural tube closure takes place during early embryogenesis and requires interactions
between genetic and environmental factors. Failure of neural tube closure is a common …

Neurulation occurs during the early embryogenesis of chordates, and it results in the
formation of the neural tube, a dorsal hollow nerve cord that constitutes the rudiment of the …

Neural tube defects (NTDs) such as spina bifida and anencephaly are common congenital
malformations in humans (1/1,000 births) that result from failure of the neural tube to close …

The number of mouse mutants and strains with neural tube defects (NTDs) now exceeds
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …

Birth defects (congenital anomalies) are the leading cause of death in babies under 1 year
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …

Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed
neural tube defects (NTD). Failure of closure of the neural tube during development results …

Bcl10, a CARD-containing protein identified from the t (1; 14)(p22; q32) breakpoint in MALT
lymphomas, has been shown to induce apoptosis and activate NF-κ B in vitro. We show that …

The head is anatomically the most sophisticated part of the body and its evolution was
fundamental to the origin of vertebrates; understanding its development is a formidable …