Spatiotemporal transcriptomic map of ischemic brain injury

D Zucha, P Abaffy, D Kirdajova, D Jirak, M Anderova… - bioRxiv, 2023 - biorxiv.org
The role of non-neuronal cells in the resolution of cerebral ischemia remains to be fully
understood. To decode key cellular processes that occur after ischemia, we performed …

[图书][B] Navigating the oligodendroglial chromatin landscape using high-throughput single-cell epigenomics

M Kabbe - 2024 - openarchive.ki.se
The central nervous system (CNS), which includes the brain and spinal cord, is a remarkably
complex system composed of billions of cells controlling everything ranging from basic …

Heterogeneity and regulation of oligodendrocyte morphology

Y Osanai, R Yamazaki, Y Shinohara… - Frontiers in Cell and …, 2022 - frontiersin.org
Oligodendrocytes form multiple myelin sheaths in the central nervous system (CNS), which
increase nerve conduction velocity and are necessary for basic and higher brain functions …

A molecularly-defined non-redundant subpopulation of OPCs controls the generation of myelinating oligodendrocytes during postnatal development.

S Moghimyfiroozabad, MA Paul, L Bellenger, F Selimi - bioRxiv, 2023 - biorxiv.org
Oligodendrocyte precursor cells (OPCs) are a class of glial cells that uniformly tiles the
whole central nervous system. They play several key functions across the brain including the …

The Cell Subtypes Selection by Genes (CSSG) algorithm for discovering cell populations in high resolution

J Kubiś, M Figiel - bioRxiv, 2023 - biorxiv.org
The recent massive improvements in transcriptomics and single-cell technologies have led
to a rising volume of data and demand for advances in bioinformatics processing. Existing …

2-Methoxyestradiol, an Endogenous 17β-Estradiol Metabolite, Induces Antimitogenic and Apoptotic Actions in Oli-Neu–Oligodendroglial Precursor Cells and Triggers …

SA Schaufelberger, M Schaettin, G Azzarito, M Rosselli… - 2024 - preprints.org
Abnormal growth of oligodendrocyte precursor cells (OPCs) importantly contributes to the
progression of glioblastoma tumors. Hence, molecules that block OPC growth may be of …

转录水平上许旺细胞髓鞘形成和节点形成的协调

F Fröb, M Wegner - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Formation of the node of Ranvier as a highly coordinated event: Saltatory conduction
ensures that information in the vertebrate nervous system is rapidly transmitted over large …

Heterogeneity and molecular programming of progenitors for motor neurons and oligodendrocytes

L Xing, R Chai, J Wang, J Lin, H Li, Y Wang, B Lai… - bioRxiv, 2021 - biorxiv.org
The pMN domain is a restricted domain in the ventral spinal cords, defined by the
expression of olig2 gene. The fate determination of pMN progenitors is highly temporally …

Novel insights into oligodendrocyte biology from developmental myelination studies in autophagy deficient mice and analysis of oligodendrocyte translatome …

MD Forston - 2023 - ir.library.louisville.edu
Loss of myelin causes severe neurological disorders and functional deficits in white matter
injuries (WMI) such as traumatic spinal cord injury (SCI). This dissertation is focused on …

[HTML][HTML] РНК-секвенирование и пространственная транскриптомика при травме спинного мозга (обзор)

ЮА Челышев, ИЛ Ермолин - Современные технологии в …, 2023 - cyberleninka.ru
Для понимания фундаментальных механизмов функционирования спинного мозга
необходимо выявить полный набор клеточных типов и образуемых ими популяций …