Controversies in primary treatment of low-risk papillary thyroid cancer

DSA McLeod, AM Sawka, DS Cooper - The Lancet, 2013 - thelancet.com
In many parts of the world, incidence of papillary thyroid cancer is increasing faster than any
other malignancy. Most papillary thyroid cancers that are diagnosed are small and are …

[HTML][HTML] Risk factors for central lymph node metastasis in CN0 papillary thyroid carcinoma: a systematic review and meta-analysis

W Sun, X Lan, H Zhang, W Dong, Z Wang, L He… - PloS one, 2015 - journals.plos.org
Background Central lymph node metastasis (CLNM) is common in papillary thyroid
carcinoma (PTC). Prophylactic central lymph node dissection (PCLND) for patients with …

[HTML][HTML] Lateral lymph node metastasis in papillary thyroid carcinoma: a systematic review and meta-analysis for prevalence, risk factors, and location

YK So, MJ Kim, S Kim, YI Son - International Journal of Surgery, 2018 - Elsevier
Background Lymph node metastasis (LNM) is frequent in papillary thyroid carcinoma (PTC)
and is associated with a poor prognosis. Unlike central LNM (CLNM), there are few studies …

Natural history of thyroid cancer

T Takano - Endocrine journal, 2017 - jstage.jst.go.jp
Thyroid cancers have long been considered to arise in middle age and, after their repeated
proliferation, resulting in further damage to the genome, they progress to more aggressive …

Phase II efficacy and pharmacogenomic study of Selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular …

DN Hayes, AS Lucas, T Tanvetyanon… - Clinical Cancer …, 2012 - AACR
Purpose: A multicenter, open-label, phase II trial was conducted to evaluate the efficacy,
safety, and tolerability of selumetinib in iodine-refractory papillary thyroid cancer (IRPTC) …

Subgroup analysis of Japanese patients in a phase 3 study of lenvatinib in radioiodine‐refractory differentiated thyroid cancer

N Kiyota, M Schlumberger, K Muro, Y Ando… - Cancer …, 2015 - Wiley Online Library
Lenvatinib significantly prolonged progression‐free survival (PFS) versus placebo in
patients with radioiodine‐refractory differentiated thyroid cancer (RR‐DTC) in the phase 3 …

Multifocality, but not bilaterality, is a predictor of disease recurrence/persistence of papillary thyroid carcinoma

HJ Kim, SY Sohn, HW Jang, SW Kim… - World journal of …, 2013 - Wiley Online Library
Background Although papillary thyroid carcinoma (PTC) often presents as multifocal or
bilateral tumors, but whether multifocality or bilaterality is associated with disease …

[HTML][HTML] Molecular classification of follicular thyroid carcinoma based on TERT promoter mutations

H Park, HC Shin, H Yang, J Heo, CS Ki, HS Kim… - Modern Pathology, 2022 - Elsevier
Follicular thyroid carcinoma (FTC) has different clinicopathological characteristics than
papillary thyroid carcinoma. However, there are no independent systems to predict cancer …

Treatment strategies for radioactive iodine-refractory differentiated thyroid cancer

F Worden - Therapeutic advances in medical oncology, 2014 - journals.sagepub.com
Until recently, no truly effective treatment options have existed for patients with radioactive
iodine (RAI)-refractory differentiated thyroid cancer (DTC), a serious disease with poor …

[HTML][HTML] Coexistence of chronic lymphocytic thyroiditis with papillary thyroid carcinoma: clinical manifestation and prognostic outcome

JS Jeong, HK Kim, CR Lee, S Park… - Journal of Korean …, 2012 - ncbi.nlm.nih.gov
The study aimed to identify the clinical characteristics of coexisting chronic lymphocytic
thyroiditis (CLT) in papillary thyroid carcinoma (PTC) and to evaluate the influence on …