Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

[HTML][HTML] Transport of intensity diffraction tomography with non-interferometric synthetic aperture for three-dimensional label-free microscopy

J Li, N Zhou, J Sun, S Zhou, Z Bai, L Lu… - Light: Science & …, 2022 - nature.com
We present a new label-free three-dimensional (3D) microscopy technique, termed transport
of intensity diffraction tomography with non-interferometric synthetic aperture (TIDT-NSA) …

Measurement of tissue optical properties in a wide spectral range: a review

IS Martins, HF Silva, EN Lazareva… - Biomedical Optics …, 2023 - opg.optica.org
A distinctive feature of this review is a critical analysis of methods and results of
measurements of the optical properties of tissues in a wide spectral range from deep UV to …

[HTML][HTML] Roadmap on wavefront shaping and deep imaging in complex media

S Gigan, O Katz, HB De Aguiar… - Journal of Physics …, 2022 - iopscience.iop.org
The last decade has seen the development of a wide set of tools, such as wavefront
shaping, computational or fundamental methods, that allow us to understand and control …

[HTML][HTML] Bond-selective intensity diffraction tomography

J Zhao, A Matlock, H Zhu, Z Song, J Zhu… - Nature …, 2022 - nature.com
Recovering molecular information remains a grand challenge in the widely used
holographic and computational imaging technologies. To address this challenge, we …

[HTML][HTML] In-silico clearing approach for deep refractive index tomography by partial reconstruction and wave-backpropagation

O Yasuhiko, K Takeuchi - Light: Science & Applications, 2023 - nature.com
Refractive index (RI) is considered to be a fundamental physical and biophysical parameter
in biological imaging, as it governs light-matter interactions and light propagation while …

[HTML][HTML] Mapping nanoscale topographic features in thick tissues with speckle diffraction tomography

S Kang, R Zhou, M Brelen, HK Mak, Y Lin… - Light: Science & …, 2023 - nature.com
Resolving three-dimensional morphological features in thick specimens remains a
significant challenge for label-free imaging. We report a new speckle diffraction tomography …

Towards in-vivo label-free detection of brain tumor margins with epi-illumination tomographic quantitative phase imaging

PC Costa, Z Guang, P Ledwig, Z Zhang… - Biomedical Optics …, 2021 - opg.optica.org
Brain tumor surgery involves a delicate balance between maximizing the extent of tumor
resection while minimizing damage to healthy brain tissue that is vital for neurological …

Label-and slide-free tissue histology using 3D epi-mode quantitative phase imaging and virtual hematoxylin and eosin staining

TM Abraham, PC Costa, C Filan, Z Guang, Z Zhang… - Optica, 2023 - opg.optica.org
Histological staining of tissue biopsies, especially hematoxylin and eosin (H&E) staining,
serves as the benchmark for disease diagnosis and comprehensive clinical assessment of …

In vivo optical trapping of erythrocytes in mouse liver imaged with oblique back-illumination microscopy

M Shao, R Liu, C Li, Z Chai, Z Zhong, F Lu… - Applied Physics …, 2023 - pubs.aip.org
Optical tweezers are ideal tools for cell manipulation in vivo due to their non-contact trapping
ability. In the current studies, the optical trapping of cells can only be achieved in light …