Epidemiology, treatment, and prevention of human T-cell leukemia virus type 1-associated diseases

DU Gonçalves, FA Proietti, JGR Ribas… - Clinical microbiology …, 2010 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1), the first human retrovirus to be discovered, is
present in diverse regions of the world, where its infection is usually neglected in health care …

Viral oncology: molecular biology and pathogenesis

UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

HTLV-1 bZIP Factor Induces T-Cell Lymphoma and Systemic Inflammation In Vivo

Y Satou, J Yasunaga, T Zhao, M Yoshida… - PLoS …, 2011 - journals.plos.org
Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of
CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 …

Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy

M Matsuoka, KT Jeang - Oncogene, 2011 - nature.com
The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be
causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has …

Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis

G Ma, J Yasunaga, M Matsuoka - Retrovirology, 2016 - Springer
Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus responsible for the
development of adult T-cell leukemia (ATL). Although HTLV-1 harbors an oncogene, tax …

Inflammatory manifestations of HTLV-1 and their therapeutic options

F Martin, GP Taylor, S Jacobson - Expert review of clinical …, 2014 - Taylor & Francis
Human T lymphotropic virus type 1 (HTLV-1) is one of the most intriguing retroviruses
infecting humans. Most commonly, infection remains undetected, since it does not cause …

Tropical spastic paraparesis and HTLV-1 associated myelopathy: clinical, epidemiological, virological and therapeutic aspects

A Gessain, R Mahieux - Revue neurologique, 2012 - Elsevier
In 1980, HumanT cell leukemia/lymphoma virus type 1 (HTLV-1) was the first oncogenic
human retrovirus to be discovered. HTLV-1 belongs to the Retroviridae family, the …

The HBZ gene, a key player in HTLV-1 pathogenesis

M Matsuoka, PL Green - Retrovirology, 2009 - Springer
Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL)
and is also associated with a variety of lymphocyte-mediated diseases. The HTLV-1 basic …

HLA class I binding of HBZ determines outcome in HTLV-1 infection

A MacNamara, A Rowan, S Hilburn, U Kadolsky… - PLoS …, 2010 - journals.plos.org
CD8+ T cells can exert both protective and harmful effects on the virus-infected host.
However, there is no systematic method to identify the attributes of a protective CD8+ T cell …

[HTML][HTML] Single-cell heterogeneity and cell-cycle-related viral gene bursts in the human leukaemia virus HTLV-1

MR Billman, D Rueda, CRM Bangham - Wellcome open research, 2017 - ncbi.nlm.nih.gov
Background: The human leukaemia virus HTLV-1 expresses essential accessory genes that
manipulate the expression, splicing and transport of viral mRNAs. Two of these genes, tax …