Acylcarnitines: nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials
M Dambrova, M Makrecka-Kuka, J Kuka… - Pharmacological …, 2022 - ASPET
Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …
metabolism pathways. They have historically been used as important diagnostic markers for …
[HTML][HTML] PGC-1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism
S Rius-Pérez, I Torres-Cuevas, I Millán… - … medicine and cellular …, 2020 - hindawi.com
Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α is a transcriptional
coactivator described as a master regulator of mitochondrial biogenesis and function …
coactivator described as a master regulator of mitochondrial biogenesis and function …
Skeletal muscle alterations in patients with acute Covid‐19 and post‐acute sequelae of Covid‐19
Skeletal muscle‐related symptoms are common in both acute coronavirus disease (Covid)‐
19 and post‐acute sequelae of Covid‐19 (PASC). In this narrative review, we discuss …
19 and post‐acute sequelae of Covid‐19 (PASC). In this narrative review, we discuss …
[HTML][HTML] Mitochondrial adaptation in cancer drug resistance: Prevalence, mechanisms, and management
P Jin, J Jiang, L Zhou, Z Huang… - … of Hematology & …, 2022 - jhoonline.biomedcentral.com
Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …
underlying stress adaptation of cancer cells in response to therapy-induced hostile …
L-carnitine and acylcarnitines: mitochondrial biomarkers for precision medicine
MR McCann, MV George De la Rosa, GR Rosania… - Metabolites, 2021 - mdpi.com
Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …
movement. Modern advances in the field of metabolomics afford the opportunity to readily …
[PDF][PDF] Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals
Time-restricted feeding (TRF) is an emerging behavioral nutrition intervention that involves a
daily cycle of feeding and fasting. In both animals and humans, TRF has pleiotropic health …
daily cycle of feeding and fasting. In both animals and humans, TRF has pleiotropic health …
[HTML][HTML] The Role of l-Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation
MA Virmani, M Cirulli - International journal of molecular sciences, 2022 - mdpi.com
Mitochondria control cellular fate by various mechanisms and are key drivers of cellular
metabolism. Although the main function of mitochondria is energy production, they are also …
metabolism. Although the main function of mitochondria is energy production, they are also …
Effect of exercise on cardiometabolic health of adults with overweight or obesity: Focus on blood pressure, insulin resistance, and intrahepatic fat—A systematic review …
F Battista, A Ermolao, MA van Baak… - Obesity …, 2021 - Wiley Online Library
This systematic review examined the impact of exercise intervention programs on selected
cardiometabolic health indicators in adults with overweight or obesity. Three electronic …
cardiometabolic health indicators in adults with overweight or obesity. Three electronic …
Atherogenic lipoprotein (a) increases vascular glycolysis, thereby facilitating inflammation and leukocyte extravasation
JG Schnitzler, RM Hoogeveen, L Ali… - Circulation …, 2020 - Am Heart Assoc
Rationale: Patients with elevated levels of lipoprotein (a)[Lp (a)] are hallmarked by
increased metabolic activity in the arterial wall on positron emission tomography/computed …
increased metabolic activity in the arterial wall on positron emission tomography/computed …
[HTML][HTML] Prehabilitation, enhanced recovery after surgery, or both? A narrative review
C Gillis, O Ljungqvist, F Carli - British journal of anaesthesia, 2022 - Elsevier
This narrative review presents a biological rationale and evidence to describe how the
preoperative condition of the patient contributes to postoperative morbidity. Any preoperative …
preoperative condition of the patient contributes to postoperative morbidity. Any preoperative …