The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone of the
clinical management of gout and conditions associated with hyperuricemia for several …

Vasculitis is inflammation of vessel walls. It has many causes, although they result in only a
few histologic patterns of vascular inflammation. Vessels of any type in any organ can be …

A drug provocation test (DPT) is the controlled administration of a drug in order to diagnose
drug hypersensitivity reactions. DPTs are performed under medical surveillance, whether …

Purpose: Lamotrigine (LTG) is an antiepileptic drug (AED) recently released in several
countries. It is effective for a variety of seizure types in adults and children both as an add‐on …

Background: Because minocycline can cause serious adverse events including
hypersensitivity syndrome reaction (HSR), serum sicknesslike reaction (SSLR), and …

Background The most frequent side‐effects of drug therapy are skin eruptions. Their
pathomechanism is rather unclear. Objective In this prospective study we investigated the T …

The study was conducted in healthy male volunteers to evaluate the absorption, metabolic
pattern, and mode of elimination of telmisartan, a nonpeptide angiotensin II receptor …

Background: Minocycline has been reported to cause serious, albeit rare, adverse events,
including serum sickness—like reaction, hypersensitivity syndrome reaction, and drug …

Data on the effects of antiepileptic drugs on the immune system are frequently inconsistent
and sometimes conflicting because the effects of drugs cannot be separated from those of …

Stevens-Johnson syndrome (SJS) is a severe cutaneous eruption that can be a life-
threatening emergency. Previously, we have reported our favorable experience in treating …