Abstract The human gammaherpesviruses Epstein–Barr virus (EBV) and Kaposi's sarcoma-
associated herpesvirus (KSHV) establish long-term latent infections associated with diverse …

Highlights•Gammaherpesviruses can adopt a variety of gene expression patterns during
latent infection.•Gene expression patterns correlate with changes in epigenetic …

A hallmark of EBV infections is its latent phase, when all viral lytic genes are repressed.
Repression results from a high nucleosome occupancy and epigenetic silencing by cellular …

ABSTRACT The Epstein-Barr virus (EBV) immediate-early protein BZLF1 (Z) mediates the
switch between latent and lytic EBV infection. Z not only activates early lytic viral gene …

Epstein-Barr virus (EBV) encoded transcription factor Zta (BZLF1, ZEBRA, EB1) is the
prototype of a class of transcription factor (including C/EBPalpha) that interact with CpG …

Viruses have evolved with their hosts, which include all living species. This has been partly
responsible for the development of highly advanced immune systems in the hosts. However …

ABSTRACT The Epstein-Barr virus (EBV) genome sustains substantial epigenetic
modification involving chromatin remodelling and DNA methylation during lytic replication …

DNA methylation normally leads to silencing of gene expression but Epstein–Barr virus
(EBV) provides an exception to the epigenetic paradigm. DNA methylation is absolutely …

Activation of the host gene egr1 is essential for the lytic replication of Epstein–Barr virus
(EBV). egr1 is activated by Zta (BZLF1, ZEBRA). Zta interacts directly with DNA through a …

Epstein-Barr virus (EBV) infection has been implicated in the aetiopathogenic mechanisms
of several neoplastic and non-neoplastic disorders. Although the precise mechanisms of the …