Antileishmanial drug discovery and development: time to reset the model?

AI Olias-Molero, C de la Fuente, M Cuquerella… - Microorganisms, 2021 - mdpi.com
Leishmaniasis is a vector-borne parasitic disease caused by Leishmania species. The
disease affects humans and animals, particularly dogs, provoking cutaneous …

Reviewing the Etiologic Agents, Microbe‐Host Relationship, Immune Response, Diagnosis, and Treatment in Chromoblastomycosis

LFD Passero, IN Cavallone… - Journal of immunology …, 2021 - Wiley Online Library
Chromoblastomycosis (CBM) is a neglected human disease, caused by different species of
pigmented dematiaceous fungi that cause subcutaneous infections. This disease has been …

Recent advances in chemotherapeutics for leishmaniasis: Importance of the cellular biochemistry of the parasite and its molecular interaction with the host

R Singh, M Kashif, P Srivastava, PP Manna - Pathogens, 2023 - mdpi.com
Leishmaniasis, a category 1 neglected protozoan disease caused by a kinetoplastid
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …

Metabolomics insights into the polyketide-lactones produced by Diaporthe caliensis sp. nov., an endophyte of the medicinal plant Otoba gracilipes

E Charria-Girón, Y Marin-Felix, U Beutling… - Microbiology …, 2023 - Am Soc Microbiol
Plants of the genus Otoba have been the basis for the treatment of tropical diseases in
indigenous communities of countries like Colombia. Despite the lack of knowledge about …

Treating leishmaniasis in Amazonia, part 2: Multi-target evaluation of widely used plants to understand medicinal practices

E Houël, M Ginouves, N Azas, E Bourreau… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Leishmaniasis are widely distributed among tropical and
subtropical countries, and remains a crucial health issue in Amazonia. Indigenous groups …

Nanostructured lipid carriers as robust systems for lupeol delivery in the treatment of experimental visceral leishmaniasis

JA Jesus, TNF da Silva, IMO Sousa, AF Ferreira… - Pharmaceuticals, 2023 - mdpi.com
Leishmaniasis is a neglected tropical disease that affects millions of people around the
world. Available therapy causes severe side effects, has unacceptable prices for some …

High Selectivity of 8-Hydroxyquinoline on Leishmania (Leishmania) and Leishmania (Viannia) Species Correlates with a Potent Therapeutic Activity In Vivo

SKS Lima, JA Jesus, C Raminelli, MD Laurenti… - Pharmaceuticals, 2023 - mdpi.com
Leishmaniasis is a neglected disease caused by protozoa of the genus Leishmania, which
causes different clinical manifestations. Drugs currently used in the treatment such as …

Overview of Research on Leishmaniasis in Africa: Current Status, Diagnosis, Therapeutics, and Recent Advances Using By-Products of the Sargassaceae Family

FM Abdoul-Latif, K Oumaskour, N Abdallah, A Ainane… - Pharmaceuticals, 2024 - mdpi.com
Leishmaniasis in Africa, which has been designated as a priority neglected tropical disease
by various global organizations, exerts its impact on millions of individuals, primarily …

[HTML][HTML] Repellent and insecticidal activities of vegetal material against sand fly populations (Diptera: Psychodidae): Systematic review and Meta-analysis

M Amane, M Echchakery, Z Dardona, M Hafidi… - Scientific African, 2023 - Elsevier
Leishmaniasis is a vector-borne disease that is widely distributed among humans and
animals, transmitted by a bite of an infected female phlebotomine sand fly (Diptera …

Treatment progress of cryptozoospermia with Western Medicine and traditional Chinese medicine: A literature review

H Liu, Z Luo, J Chen, H Zheng… - Health Science Reports, 2023 - Wiley Online Library
Abstract Background and Aims Cryptozoospermia is an extreme oligozoospermia with an
unsatisfactory treatment effect, with an incidence rate of approximately 8.73% in male …