The molecular biology of carcinogenesis

HC Pitot - Cancer, 1993 - Wiley Online Library
Carcinogenesis may result from the action of any one or a combination of chemical,
physical, biologic, and/or genetic insults to cells. The process of carcinogenesis may be …

[图书][B] Biomarkers: biochemical, physiological, and histological markers of anthropogenic stress

RJ Huggett - 2018 - books.google.com
This book provides a survey of biochemical, physiological and histological biomarkers of
environmental stress, along with evaluations of the strengths and weaknesses of various …

Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes

LM Sargent, DW Porter, LM Staska, AF Hubbs… - Particle and fibre …, 2014 - Springer
Background Engineered carbon nanotubes are currently used in many consumer and
industrial products such as paints, sunscreens, cosmetics, toiletries, electronic processes …

Animal studies addressing the carcinogenicity of TCDD (or related compounds) with an emphasis on tumour promotion

YP Dragan, D Schrenk - Food Additives & Contaminants, 2000 - Taylor & Francis
Dioxin and certain structurally related compounds increase the incidence of liver neoplasms
in rodents upon chronic bioassay. Short-term studies indicate the lack of direct DNA …

Histopathologic biomarkers

DE Hinton, PC Baumann, GR Gardner, WE Hawkins… - …, 2018 - taylorfrancis.com
Histopathologic alterations in fish tissues are biomarkers of effect of exposure to
environmental stressors. This category of biomarkers has the advantage of allowing one to …

New analysis of a rat feeding study with a genetically modified maize reveals signs of hepatorenal toxicity

GE Séralini, D Cellier, JS de Vendomois - Archives of environmental …, 2007 - Springer
Health risk assessment of genetically modified organisms (GMOs) cultivated for food or feed
is under debate throughout the world, and very little data have been published on mid-or …

Genotoxicity of multi-walled carbon nanotubes at occupationally relevant doses

KJ Siegrist, SH Reynolds, ML Kashon… - Particle and fibre …, 2014 - Springer
Carbon nanotubes are commercially-important products of nanotechnology; however, their
low density and small size makes carbon nanotube respiratory exposures likely during their …

Single-walled carbon nanotube-induced mitotic disruption

LM Sargent, AF Hubbs, SH Young, ML Kashon… - … /Genetic Toxicology and …, 2012 - Elsevier
Carbon nanotubes were among the earliest products of nanotechnology and have many
potential applications in medicine, electronics, and manufacturing. The low density, small …

Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms

A Bishayee, D Bhatia, RJ Thoppil, AS Darvesh… - …, 2011 - academic.oup.com
Hepatocellular carcinoma (HCC), one of the most prevalent and lethal cancers, has shown
an alarming rise in the USA. Without effective therapy for HCC, novel chemopreventive …

Induction of aneuploidy by single‐walled carbon nanotubes

LM Sargent, AA Shvedova, AF Hubbs… - Environmental and …, 2009 - Wiley Online Library
Engineered carbon nanotubes are newly emerging manufactured particles with potential
applications in electronics, computers, aerospace, and medicine. The low density and small …