Follicular lymphoma

A Carbone, S Roulland, A Gloghini, A Younes… - Nature reviews Disease …, 2019 - nature.com
Follicular lymphoma (FL) is a systemic neoplasm of the lymphoid tissue displaying germinal
centre (GC) B cell differentiation. FL represents~ 5% of all haematological neoplasms and …

Follicular lymphoma: evolving therapeutic strategies

BS Kahl, DT Yang - Blood, The Journal of the American Society …, 2016 - ashpublications.org
Follicular lymphoma (FL) is the most common indolent non-Hodgkin lymphoma in the
Western hemisphere. After decades of stagnation, the natural history of FL appears to have …

Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA

F Scherer, DM Kurtz, AM Newman, H Stehr… - Science translational …, 2016 - science.org
Patients with diffuse large B cell lymphoma (DLBCL) exhibit marked diversity in tumor
behavior and outcomes, yet the identification of poor-risk groups remains challenging. In …

Follicular lymphoma in the modern era: survival, treatment outcomes, and identification of high-risk subgroups

CL Batlevi, F Sha, A Alperovich, A Ni, K Smith… - Blood cancer …, 2020 - nature.com
Patients with follicular lymphoma (FL) frequently require multiple treatments during their
disease course; however, survival based on lines of treatment remains poorly described in …

Cause of death in follicular lymphoma in the first decade of the rituximab era: a pooled analysis of French and US cohorts

C Sarkozy, MJ Maurer, BK Link… - Journal of Clinical …, 2019 - ascopubs.org
Purpose Although the life expectancy of patients with follicular lymphoma (FL) has
increased, little is known of their causes of death (CODs) in the rituximab era. Patients and …

High rate of durable complete remission in follicular lymphoma after CD19 CAR-T cell immunotherapy

AV Hirayama, J Gauthier, KA Hay… - Blood, The Journal …, 2019 - ashpublications.org
Patients with follicular lymphoma (FL) with early relapse after initial chemoimmunotherapy,
refractory disease, or histologic transformation (tFL) have limited progression-free and …

Histological transformation and progression in follicular lymphoma: a clonal evolution study

R Kridel, FC Chan, A Mottok, M Boyle, P Farinha… - PLoS …, 2016 - journals.plos.org
Background Follicular lymphoma (FL) is an indolent, yet incurable B cell malignancy. A
subset of patients experience an increased mortality rate driven by two distinct clinical end …

NCCN guidelines insights: B-cell lymphomas, version 3.2019: featured updates to the NCCN guidelines

AD Zelenetz, LI Gordon, JS Abramson… - Journal of the National …, 2019 - jnccn.org
Diffuse large B-cell lymphomas (DLBCLs) and follicular lymphoma (FL) are the most
common subtypes of B-cell non-Hodgkin's lymphomas in adults. Histologic transformation of …

Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels

T Roider, J Seufert, A Uvarovskii, F Frauhammer… - Nature cell …, 2020 - nature.com
Tumour heterogeneity encompasses both the malignant cells and their microenvironment.
While heterogeneity between individual patients is known to affect the efficacy of cancer …

Risk factors and outcomes for patients with follicular lymphoma who had histologic transformation after response to first-line immunochemotherapy in the PRIMA trial

C Sarkozy, M Trneny, L Xerri, N Wickham… - Journal of Clinical …, 2016 - ascopubs.org
Purpose To study the outcome of histologic transformation (HT) in a large prospective cohort
of patients with follicular lymphoma (FL) who previously responded to immunochemotherapy …