The Rho family of GTPases belongs to the Ras superfamily of low molecular weight (∼ 21
kDa) guanine nucleotide binding proteins. The most extensively studied members are RhoA …

As the leading cause of hospital-acquired diarrhea, Clostridium difficile colonizes the large
bowel of patients undergoing antibiotic therapy and produces two toxins, which cause …

Certain pathogenic species of Bacillus and Clostridium have developed unique methods for
intoxicating cells that employ the classic enzymatic “AB” paradigm for protein toxins. The …

Anthocyanins are being increasingly investigated for their neuroprotective and
antineuroinflammatory effects; however, the overall bioavailability of many anthocyanins is …

Epigallocatechin gallate (EGCG) is a flavonoid belonging to the chemical class of falvan-3-
ols (catechins) esterified with gallic acid. It is the main catechin found in green tea (Camellia …

Neuronal migration and axon growth, key events during neuronal development, require
distinct changes in the cytoskeleton. Although many molecular regulators of polarity have …

Epigallocatechin-3-gallate (EGCG) is a major flavonoid component of green tea that
displays antiapoptotic effects in numerous models of neurotoxicity. Although the intrinsic free …

Border cell migration in the Drosophila ovary is a relatively simple and genetically tractable
model for studying the conversion of epithelial cells to migratory cells. Like many cell …

Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical
and medical applications. Despite growing scientific, medical, and industrial interest …

Toxins are potent molecules used by various bacteria to interact with a host organism. Some
of them specifically act on neuronal cells (clostridial neurotoxins) leading to characteristics …