Hypercholesterolemia is a strong determinant of mortality and morbidity associated with
cardiovascular diseases and a major contributor to the global disease burden. Mutations in …

Rapid progress in human genome decoding has accelerated search for the role of gene
polymorphisms in the pathogenesis of complex multifactorial diseases. This review …

Genome-wide association studies (GWASs) have identified many SNPs underlying
variations in plasma-lipid levels. We explore whether additional loci associated with plasma …

APOA1 and APOB are the structural proteins of high-density lipoprotein and APOB-
containing lipoproteins, such as low-density lipoprotein and very low-density lipoprotein …

Essential fatty acids (EFA) and conjugated linoleic acids (CLA) are unsaturated fatty acids
with immune-modulatory effects, yet their synergistic effect is poorly understood in dairy …

Several apolipoprotein genes are located at the APOE locus on chromosome 19q13. 32.
This study explored the genetic determinants of cardiometabolic traits and metabolic …

Numerous researches supported that non-alcoholic fatty liver disease (NAFLD) was an
emerging problem associated with increased visceral adiposity (obesity), diabetes and …

The role of common APOE variants on plasma lipids, particularly low density lipoprotein
(LDL) levels, and coronary heart disease (CHD) risk is well known; the influence of variation …

Background Multiple observational studies have reported substantial comorbidity between
neuropsychiatric disorders and cardiovascular disease (CVD), but the underlying …

Biochemical studies of lipoproteins have shed light on their composition, highly contributing
to the comprehension of their function. Due to the complexity of their structure, however, an …