The changing therapeutic landscape of head and neck cancer
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …
The clinical impact of HPV tumor status upon head and neck squamous cell carcinomas
Human papillomavirus (HPV) is etiologically responsible for a distinct subset of head and
neck squamous cell cancers (HNSCCs). HPV-positive HNSCCs (HPV-HNSCCs) most …
neck squamous cell cancers (HNSCCs). HPV-positive HNSCCs (HPV-HNSCCs) most …
Deintensification candidate subgroups in human papillomavirus–related oropharyngeal cancer according to minimal risk of distant metastasis
Purpose To define human papillomavirus (HPV)–positive oropharyngeal cancers (OPC)
suitable for treatment deintensification according to low risk of distant metastasis (DM) …
suitable for treatment deintensification according to low risk of distant metastasis (DM) …
Pretreatment identification of head and neck cancer nodal metastasis and extranodal extension using deep learning neural networks
Identification of nodal metastasis and tumor extranodal extension (ENE) is crucial for head
and neck cancer management, but currently only can be diagnosed via postoperative …
and neck cancer management, but currently only can be diagnosed via postoperative …
Multi-institutional validation of deep learning for pretreatment identification of extranodal extension in head and neck squamous cell carcinoma
BH Kann, DF Hicks, S Payabvash… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Extranodal extension (ENE) is a well-established poor prognosticator and an
indication for adjuvant treatment escalation in patients with head and neck squamous cell …
indication for adjuvant treatment escalation in patients with head and neck squamous cell …
A systematic review of transoral robotic surgery and radiotherapy for early oropharynx cancer: a systematic review
JR De Almeida, JK Byrd, R Wu, CL Stucken… - The …, 2014 - Wiley Online Library
Objectives/Hypothesis To demonstrate the comparative effectiveness of transoral robotic
surgery (TORS) to intensity modulated radiotherapy (IMRT) for early T‐stage oropharyngeal …
surgery (TORS) to intensity modulated radiotherapy (IMRT) for early T‐stage oropharyngeal …
Impact of Neoadjuvant Durvalumab with or without Tremelimumab on CD8+ Tumor Lymphocyte Density, Safety, and Efficacy in Patients with Oropharynx Cancer …
R Ferrarotto, D Bell, ML Rubin, KA Hutcheson… - Clinical Cancer …, 2020 - AACR
Purpose: In oropharyngeal squamous cell carcinoma (OPC), high CD8+ tumor-infiltrating
lymphocyte (CD8+ TIL) density confers improved prognosis. We compared neoadjuvant …
lymphocyte (CD8+ TIL) density confers improved prognosis. We compared neoadjuvant …
Prognostic factors and survival unique to surgically treated p16+ oropharyngeal cancer
BH Haughey, P Sinha - The Laryngoscope, 2012 - Wiley Online Library
Abstract Objectives/Hypothesis: Current head and neck epidemiology demonstrates a
steadily increasing incidence of p16+ human papillomavirus‐related oropharynx squamous …
steadily increasing incidence of p16+ human papillomavirus‐related oropharynx squamous …
The diagnostic performance of CT and MRI for detecting extranodal extension in patients with head and neck squamous cell carcinoma: a systematic review and …
Objective To review the diagnostic performance of CT and MRI for detecting extranodal
extension (ENE) in head and neck squamous cell carcinoma (HNSCC) patients. Methods …
extension (ENE) in head and neck squamous cell carcinoma (HNSCC) patients. Methods …
The role of transoral robotic surgery in the management of oropharyngeal cancer: a review of the literature
SA Dowthwaite, JH Franklin, DA Palma… - International …, 2012 - Wiley Online Library
Background. Transoral robotic surgery (TORS) is an emerging treatment option for the
treatment of head and neck malignancies, particularly for oropharyngeal squamous cell …
treatment of head and neck malignancies, particularly for oropharyngeal squamous cell …