People with schizophrenia die 1520 years prematurely. Understanding mortality risk and
aggravating/attenuating factors is essential to reduce this gap. We conducted a systematic …

Globally, too many people die prematurely from suicide and the physical comorbidities
associated with mental illness and mental distress. The purpose of this Review is to mobilise …

Schizophrenia substantially contributes to the burden of mental disorders. Schizophrenia's
burden and epidemiological estimates in some countries have been published, but updated …

We aimed to identify diagnosis-specific/transdiagnostic/transoutcome multivariable
candidate predictors (MCPs) of key outcomes in mental disorders. We conducted an …

Objective Bipolar disorder (BD) is associated with premature mortality. All-cause and
specific mortality risks in this population remain unclear, and more studies are still needed to …

Empirical evidence indicates a significant bidirectional association between mental
disorders and physical diseases, but the prospective impact of mental disorders on clinical …

We mapped the evidence on the type and strength of associations between a broad range of
mental and physical conditions in children and adolescents, by carrying out an umbrella …

Schizophrenia is a life-shortening disease and life expectancy in patients may be 15–20
years shorter than in the general population, with increasing longevity gap over time …

Objective: To investigate the association of metabolic side effects with antipsychotic dose,
we conducted a dose-response meta-analysis of randomized controlled trials (RCTs) in …

Background Patients with severe mental illness (SMI)(ie, schizophrenia, bipolar disorder, or
major depressive disorder) have been reported to have excess mortality rates from infection …