Metabolic activation of the toxic natural products from herbal and dietary supplements leading to toxicities

YK Wang, WQ Li, S Xia, L Guo, Y Miao… - Frontiers in …, 2021 - frontiersin.org
Currently, herbal and dietary supplements have been widely applied to prevent and treat
various diseases. However, the potential toxicities and adverse reactions of herbal and …

Endocrine disrupting compounds in the baby's world-A harmful environment to the health of babies

J Płotka-Wasylka, E Mulkiewicz, H Lis… - Science of The Total …, 2023 - Elsevier
Globally, there has been a significant increase in awareness of the adverse effects of
chemicals with known or suspected endocrine-acting properties on human health. Human …

DNA damage resulting from human endocrine disrupting chemical exposure: Genotoxicity, detection and dietary phytochemical intervention

X Li, N Zang, N Zhang, L Pang, L Lv, X Meng, X Lv… - Chemosphere, 2023 - Elsevier
In recent years, exposure to endocrine disrupting chemicals (EDCs) has posed an
increasing threat to human health. EDCs are major risk factors in the occurrence and …

High-throughput effect-directed analysis using downscaled in vitro reporter gene assays to identify endocrine disruptors in surface water

N Zwart, SL Nio, CJ Houtman, J De Boer… - … science & technology, 2018 - ACS Publications
Effect-directed analysis (EDA) is a commonly used approach for effect-based identification of
endocrine disruptive chemicals in complex (environmental) mixtures. However, for routine …

The role of sulfotransferases in liver diseases

Y Xie, W Xie - Drug Metabolism and Disposition, 2020 - ASPET
The cytosolic sulfotransferases (SULTs) are phase II conjugating enzymes that catalyze the
transfer of a sulfonate group from the universal sulfate donor 3′-phosphoadenosine-5 …

The negative impact of the environment on methylation/epigenetic marking in gametes and embryos: A plea for action to protect the fertility of future generations

Y Menezo, B Dale, K Elder - Molecular Reproduction and …, 2019 - Wiley Online Library
Life expectancy has increased since World War II, and this may be attributed to several
aspects of modern lifestyles. However, now we are faced with a downturn, which seems to …

Gene expression analysis of whole blood RNA from pigs infected with low and high pathogenic African swine fever viruses

C Jaing, RRR Rowland, JE Allen, A Certoma… - Scientific reports, 2017 - nature.com
African swine fever virus (ASFV) is a macrophage-tropic virus responsible for ASF, a
transboundary disease that threatens swine production world-wide. Since there are no …

Molecular mechanism of alternative P450-catalyzed metabolism of environmental phenolic endocrine-disrupting chemicals

L Ji, S Ji, C Wang, KP Kepp - Environmental science & technology, 2018 - ACS Publications
Understanding the bioactivation mechanisms to predict toxic metabolites is critical for risk
assessment of phenolic endocrine-disrupting chemicals (EDCs). One mechanism involves …

An inadvertent issue of human retina exposure to endocrine disrupting chemicals: A safety assessment

M Li, T Yang, L Gao, H Xu - Chemosphere, 2021 - Elsevier
Endocrine disrupting chemicals (EDCs) are a group of chemical compounds that present a
considerable public health problem due to their pervasiveness and associations with …

Tetrabromobisphenol A induced reproductive endocrine-disrupting effects in mussel Mytilus galloprovincialis

S Wang, C Ji, F Li, J Zhan, T Sun, J Tang… - Journal of Hazardous …, 2021 - Elsevier
Tetrabromobisphenol A (TBBPA) pollution in marine environmental media poses great risks
to marine organisms due to its potential endocrine-disrupting effects. However, limited …