Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

[HTML][HTML] The hallmarks of flavonoids in cancer

LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …

Dietary flavonoid aglycones and their glycosides: Which show better biological significance?

J Xiao - Critical reviews in food science and nutrition, 2017 - Taylor & Francis
The dietary flavonoids, especially their glycosides, are the most vital phytochemicals in diets
and are of great general interest due to their diverse bioactivity. The natural flavonoids …

Advance on the Flavonoid C-glycosides and Health Benefits

J Xiao, E Capanoglu, AR Jassbi… - Critical reviews in food …, 2016 - Taylor & Francis
The dietary flavonoids, especially their glycosides, are the most vital phytochemicals in diets
and are of great general interest due to their diverse bioactivity. Almost all natural flavonoids …

Role of oxidative stress as key regulator of muscle wasting during cachexia

J Ábrigo, AA Elorza, CA Riedel, C Vilos… - Oxidative medicine …, 2018 - Wiley Online Library
Skeletal muscle atrophy is a pathological condition mainly characterized by a loss of
muscular mass and the contractile capacity of the skeletal muscle as a consequence of …

[HTML][HTML] Targeting the interplay of autophagy and ROS for cancer therapy: An updated overview on phytochemicals

L Dong, J He, L Luo, K Wang - Pharmaceuticals, 2023 - mdpi.com
Autophagy is an evolutionarily conserved self-degradation system that recycles cellular
components and damaged organelles, which is critical for the maintenance of cellular …

Stability of dietary polyphenols under the cell culture conditions: Avoiding erroneous conclusions

J Xiao, P Högger - Journal of agricultural and food chemistry, 2015 - ACS Publications
Most data of bioactivity from dietary polyphenols have been derived from in vitro cell culture
experiments. In this context, little attention is paid to potential artifacts due to chemical …

Natural compounds modulate the crosstalk between apoptosis-and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells

C Braicu, O Zanoaga, AA Zimta, AB Tigu… - Seminars in Cancer …, 2022 - Elsevier
Due to the high number of annual cancer–related deaths, and the economic burden that this
malignancy affects today's society, the study of compounds isolated from natural sources …

Mechanism of juglone-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells

YY Zhang, F Zhang, YS Zhang, K Thakur… - Journal of agricultural …, 2019 - ACS Publications
The molecular mechanism of Juglone-induced cell cycle arrest and apoptosis in human
endometrial cancer cells was investigated. Juglone was purified from the green husk of …

[HTML][HTML] Autophagy: a potential therapeutic target of polyphenols in hepatocellular carcinoma

C Kiruthiga, KP Devi, SM Nabavi, A Bishayee - Cancers, 2020 - mdpi.com
Autophagy is a conserved biological phenomenon that maintains cellular homeostasis
through the clearing of damaged cellular components under cellular stress and offers the …