Alzheimer's disease (AD) is the most common form of dementia, which disproportionately
affects women. AD symptoms include progressive memory loss associated with amyloid-β …

Stress is a major risk factor for neurodevelopmental and neuropsychiatric disorders, with the
capacity to impact susceptibility to disease as well as long-term neurobiological and …

Perineuronal net (PNN) accumulation around parvalbumin-expressing (PV) inhibitory
interneurons marks the closure of critical periods of high plasticity, whereas PNN removal …

Alzheimer's disease (AD) is the most common neurological disease, which is associated
with gradual memory loss and correlated with synaptic hyperactivity and abnormal …

The extracellular matrix (ECM) is a fundamental component of biological tissues. The ECM
in the central nervous system (CNS) is unique in both composition and function. Functions …

Background. The extracellular matrix of the PNS/CNS is unusual in that it is dominated by
glycosaminoglycans, especially hyaluronan, whose space filling and hydrating properties …

Perineuronal nets (PNNs) are condensed extracellular matrix (ECM) structures regulating
developmental plasticity and protecting neurons against oxidative stress. PNN abnormalities …

The extracellular matrix (ECM) is a dynamic and complex network of proteins and molecules
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …

Both early life aversive experiences and intrinsic alterations in early postnatal
neurodevelopment are considered predisposing factors for psychiatric disorders, such as …

Perineuronal nets (PNNs) which mostly surround the parvalbumin (PV) neurons, have been
shown to play critical roles in neural plasticity. Recently, PNNs have been shown to regulate …