Integral membrane proteins (IMPs) fulfill important physiological functions by providing cell–
environment, cell–cell and virus–host communication; nutrients intake; export of toxic …

Fatty acid desaturase catalyzes the desaturation reactions by inserting double bonds into
the fatty acyl chain, producing unsaturated fatty acids, which play a vital part in the synthesis …

Eukaryotic cell‐free protein synthesis (CFPS) can accelerate expression and high‐
throughput analysis of complex proteins with functionally relevant post‐translational …

Cryo-electron microscopy (cryo-EM) enables the determination of membrane protein
structures in native-like environments. Characterising how membrane proteins interact with …

Membrane proteins (MPs) are essential components of all biological membranes,
contributing to key cellular functions that include signalling, molecular transport and energy …

Cryo-electron tomography (cryo-ET) combines a close-to-life preservation of the cell with
high-resolution three-dimensional (3D) imaging. This allows to study the molecular …

Integrin-mediated activation of the profibrotic mediator transforming growth factor-β1 (TGF-
β1), plays a critical role in idiopathic pulmonary fibrosis (IPF) pathogenesis. Galectin-3 is …

Protein structure prediction is one of major problems of modern biophysics: current attempts
to predict the tertiary protein structure from amino acid sequence are successful mostly when …

Highlights•Microbial cell factories are used for clean energy valorization of renewable
biomass.•Efficient conversion of biomass requires identification of novel transporters.• …

Rapid advances in cryo-electron tomography (cryo-ET) are driving a revolution in cellular
structural biology. However, unambiguous identification of specific biomolecules within …